Related references
Note: Only part of the references are listed.Design, synthesis, and Structure-Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors
Yunxin Duan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study
Theodore W. Laetsch et al.
LANCET ONCOLOGY (2018)
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children
A. Drilon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Structural characterization of nonactive site, TrkA-selective kinase inhibitors
Hua-Poo Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor
Maria Menichincheri et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications
Elena Ardini et al.
MOLECULAR CANCER THERAPEUTICS (2016)
NTRK gene fusions as novel targets of cancer therapy across multiple tumour types
Alessio Amatu et al.
ESMO OPEN (2016)
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
Robert C. Doebele et al.
CANCER DISCOVERY (2015)
Discovery of Pyrroloaminopyrazoles as Novel PAK Inhibitors
Chuangxing Guo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition
T. Bertrand et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA Inhibitors
Tao Wang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2012)
Perineural invasion and associated pain in pancreatic cancer
Aditi A. Bapat et al.
NATURE REVIEWS CANCER (2011)
Rearrangements of NTRK1 gene in papillary thyroid carcinoma
A. Greco et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Brain-Derived Neurotrophic Factor (BDNF) has Proliferative Effects on Neural Stem Cells through the Truncated TRK-B Receptor, MAP Kinase, AKT, and STAT-3 Signaling Pathways
Omedul Islam et al.
CURRENT NEUROVASCULAR RESEARCH (2009)
Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases
Tao Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Trk signaling regulates neural precursor cell proliferation and differentiation during cortical development
Katarzyna Bartkowska et al.
DEVELOPMENT (2007)
Neurotrophins and their receptors: A convergence point for many signalling pathways
MV Chao
NATURE REVIEWS NEUROSCIENCE (2003)
The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins
V Ranzi et al.
ENDOCRINOLOGY (2003)
Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc
E Roccato et al.
BRITISH JOURNAL OF CANCER (2002)
Neurotrophins: Roles in neuronal development and function
EJ Huang et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)