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FASEB JOURNAL (2012)
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JOURNAL OF TRANSLATIONAL MEDICINE (2011)
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CELL DIVISION (2010)
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma
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CANCER CELL (2009)
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Su Jung Song et al.
CANCER RESEARCH (2009)
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Teresa Sardon et al.
CHEMBIOCHEM (2009)
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Nae-Fang Twu et al.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2009)
Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival
Jin-e Yao et al.
MOLECULAR CANCER (2009)
Effects of the Aurora kinase inhibitor VX-680 on anaplastic thyroid cancer-derived cell lines
Yannick Arlot-Bonnemains et al.
ENDOCRINE-RELATED CANCER (2008)
Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts
Elisabeth Walsby et al.
HAEMATOLOGICA (2008)
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation
R. Rong et al.
ONCOGENE (2007)
VX-680 inhibits Aurora A and Aurora B kinase activity in human cells
Rebecca K. Tyler et al.
CELL CYCLE (2007)
AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo
Jing Yang et al.
BLOOD (2007)
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Mathias Schmidt et al.
DRUG RESISTANCE UPDATES (2007)
AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis
Robert W. Wilkinson et al.
CLINICAL CANCER RESEARCH (2007)
MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy
Kara Hoar et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Subcellular localization of the spindle proteins Aurora A, Mad2, and BUBR1 assessed by immunohistochemistry
Espen Burum-Auensen et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
Mark G. Manfredi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Roles of aurora kinases in mitosis and tumorigenesis
Jingyan Fu et al.
MOLECULAR CANCER RESEARCH (2007)
Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the aurora kinase inhibitor VX-680
MA Young et al.
CANCER RESEARCH (2006)
Mechanism of Aurora B activation by INCENP and inhibition by Hesperadin
F Sessa et al.
MOLECULAR CELL (2005)
Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts
BB Gadea et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis
M Tatsuka et al.
ONCOGENE (2005)
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
EA Harrington et al.
NATURE MEDICINE (2004)
The cellular geography of aurora kinases
M Carmena et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
TAC-1 and ZYG-9 form a complex that promotes microtubule assembly in C-elegans embryos
JM Bellanger et al.
CURRENT BIOLOGY (2003)
Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis
Y Minoshima et al.
DEVELOPMENTAL CELL (2003)
Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase
A Kawajiri et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
MY Tsai et al.
NATURE CELL BIOLOGY (2003)
Molecular dynamics of aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinα
K Sugimoto et al.
CELL STRUCTURE AND FUNCTION (2002)
Crystal structure of aurora-2, an oncogenic serine/threonine kinase
GMT Cheetham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
APC/Fizzy-Related targets Aurora-A kinase for proteolysis
A Castro et al.
EMBO REPORTS (2002)
Cell-cycle-dependent regulation of human aurora a transcription is mediated by periodic repression of E4TF1
M Tanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
R Giet et al.
JOURNAL OF CELL BIOLOGY (2002)
Drosophila Aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis
R Giet et al.
JOURNAL OF CELL BIOLOGY (2001)
Chromosomal passengers and the (aurora) ABCs of mitosis
RR Adams et al.
TRENDS IN CELL BIOLOGY (2001)
Mitotic kinases as regulators of cell division and its checkpoints
EA Nigg
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Myosin II regulatory light chain as a novel substrate for AIM-1, an Aurora/Ipl1p-related kinase from rat
M Murata-Hori et al.
JOURNAL OF BIOCHEMISTRY (2000)
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
RR Adams et al.
CURRENT BIOLOGY (2000)
CYK-4:: A Rho family GTPase activating protein (GAP) required for central spindle formation and cytokinesis
V Jantsch-Plunger et al.
JOURNAL OF CELL BIOLOGY (2000)
Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway
K Honda et al.
ONCOGENE (2000)