Vibrio cholerae was found in cultured bullfrog

Bullfrog is one of the most important economic aquatic animals in China that is widely cultured in southern China and is a key breed recommended as an industry of poverty alleviation in China. During recent years, a fatal bacterial disease has often been found in cultured bullfrogs. The clinical manifestations of the diseased bullfrogs were severe intestinal inflammation and an anal prolapse. A bacterial pathogen was isolated from the diseased bullfrog intestines. The bacterium was identified as Vibrio cholerae using morphological, biochemical and 16S rRNA phylogenetic analysis. In this study, V. cholerae was isolated and identified in diseased bullfrogs for the first time, providing a basis for the diagnosis and control of the disease. Therefore, attention should be paid to the modes of transmission of V. cholerae from bullfrog and formulate reasonable safety measures.

Automated summary

In recent years, a fatal bacterial disease has been frequently found in cultured bullfrogs in China, causing severe intestinal inflammation and anal prolapse. The isolated bacterial pathogen was identified as Vibrio cholerae. This study revealed the presence of V. cholerae in diseased bullfrogs for the first time, providing a basis for the diagnosis and control of the disease.