Related references
Note: Only part of the references are listed.An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex
Vania Macias-Calvio et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2021)
Development and biological evaluation of[18F]FMN3PA & [18F] FMN3PU for leucine-rich repeat kinase 2 (LRRK2) in vivo PET imaging
Noeen Malik et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
A More Homogeneous Phenotype in Parkinson's Disease Related to R1441G Mutation in the LRRK2 Gene
Ana Vinagre-Aragon et al.
FRONTIERS IN NEUROLOGY (2021)
A LRRK2 GTP Binding Inhibitor, 68, Reduces LPS-Induced Signaling Events and TNF-α Release in Human Lymphoblasts
Tianxia Li et al.
CELLS (2021)
Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes
C. Alexander Boecker et al.
CURRENT BIOLOGY (2021)
14-3-3 Proteins: Novel Pharmacological Targets in Neurodegenerative Diseases
F. Sanders Pair et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2021)
Exploring the Role of Orexinergic Neurons in Parkinson's Disease
Sachin Kumar et al.
NEUROTOXICITY RESEARCH (2021)
Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-present)
Xiao Ding et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2020)
Alpha-Synuclein and LRRK2 in Synaptic Autophagy: Linking Early Dysfunction to Late-Stage Pathology in Parkinson's Disease
Giulia Lamonaca et al.
CELLS (2020)
LRRK2 Phosphorylation, More Than an Epiphenomenon
Antoine Marchand et al.
FRONTIERS IN NEUROSCIENCE (2020)
Progress inLRRK2-Associated Parkinson's Disease Animal Models
Steven P. Seegobin et al.
FRONTIERS IN NEUROSCIENCE (2020)
Nonsteroidal Anti-Inflammatory Use and LRRK2 Parkinson's Disease Penetrance
Marta San Luciano et al.
MOVEMENT DISORDERS (2020)
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction
C. K. Deniston et al.
NATURE (2020)
Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
Joanna A. Korecka et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2020)
LRRK2 and mitochondria: Recent advances and current views
Alpana Singh et al.
BRAIN RESEARCH (2019)
A Comprehensive Analysis of Population Differences in LRRK2 Variant Distribution in Parkinson's Disease
Li Shu et al.
FRONTIERS IN AGING NEUROSCIENCE (2019)
LRRK2 in Infection: Friend or Foe?
Susanne Herbst et al.
ACS INFECTIOUS DISEASES (2019)
Synthesis and Preliminary Evaluation of [11C]GNE-1023 as a Potent PET Probe for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease
Zhen Chen et al.
CHEMMEDCHEM (2019)
Recent Developments in LRRK2-Targeted Therapy for Parkinson's Disease
Ye Zhao et al.
DRUGS (2019)
Structural and functional investigation of the Small Ribosomal Subunit Biogenesis GTPase A (RsgA) from Pseudomonas aeruginosa
Rena Rocchio et al.
FEBS JOURNAL (2019)
Basal and Evoked Neurotransmitter Levels in Parkin, DJ-1, PINK1 and LRRK2 Knockout Rat Striatum
Rose B. Creed et al.
NEUROSCIENCE (2019)
Targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of Parkinson's disease
Sofia Domingos et al.
FUTURE MEDICINAL CHEMISTRY (2019)
The role of LRRK2 in cell signalling
Kirsten Harvey et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2019)
Roco Proteins: GTPases with a Baroque Structure and Mechanism
Lina Wauters et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein Destabilization
T. De Wit et al.
MOLECULAR NEUROBIOLOGY (2019)
Crystal structure of the WD40 domain dimer of LRRK2
Pengfei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same
Daniel C. Berwick et al.
MOLECULAR NEURODEGENERATION (2019)
Autophagy and LRRK2 in the Aging Brain
Federica Albanese et al.
FRONTIERS IN NEUROSCIENCE (2019)
LRRK2 Kinase Plays an Important Role in the Intracellular Survival of Brucella abortus 2308 in Murine Macrophages and in a Mouse Infection Model
Jihai Yi et al.
PAKISTAN VETERINARY JOURNAL (2019)
LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network
Zhiyong Liu et al.
HUMAN MOLECULAR GENETICS (2018)
Role of LRRK2 in manganese-induced neuroinflammation and microglial autophagy
Jiayan Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Chemoproteomics Reveals the Antiproliferative Potential of Parkinson's Disease Kinase Inhibitor LRRK2-IN-1 by Targeting PCNA Protein
Weichao Li et al.
MOLECULAR PHARMACEUTICS (2018)
The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition
Kaela Kelly et al.
EXPERIMENTAL NEUROLOGY (2018)
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease
Cornelis Blauwendraat et al.
JAMA NEUROLOGY (2018)
Mitochondrial network structure homeostasis and cell death
Long-long Xie et al.
CANCER SCIENCE (2018)
Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage
Irene H. Flones et al.
ACTA NEUROPATHOLOGICA (2018)
Effects of LRRK2 Inhibitors on Nigrostriatal Dopaminergic Neurotransmission
Qi Qin et al.
CNS NEUROSCIENCE & THERAPEUTICS (2017)
Targeting LRRK2 in Parkinson's disease: an update on recent developments
Sharon L. Chan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2017)
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Jack D. Scott et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment
Joseph M. Thomas et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis
Martin Steger et al.
ELIFE (2017)
Rab GTPases in Immunity and Inflammation
Akriti Prashar et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons
Andrew J. Schwab et al.
STEM CELL REPORTS (2017)
Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration
Heather M. Wilkins et al.
FRONTIERS IN IMMUNOLOGY (2017)
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease
Fanpeng Zhao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
LRRK2 levels in immune cells are increased in Parkinson'sdisease
D. A. Cook et al.
NPJ PARKINSONS DISEASE (2017)
14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening
Nicholas J. Lavalley et al.
HUMAN MOLECULAR GENETICS (2016)
Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition
G. A. Smith et al.
MOLECULAR NEUROBIOLOGY (2016)
Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease
S. Kim et al.
MOLECULAR PSYCHIATRY (2016)
The unconventional G-protein cycle of LRRK2 and Roco proteins
Susanne Terheyden et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia
Tatsunori Maekawa et al.
BMC NEUROSCIENCE (2016)
G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons
Laura A. Volpicelli-Daley et al.
JOURNAL OF NEUROSCIENCE (2016)
DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study
Joanne Trinh et al.
LANCET NEUROLOGY (2016)
Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF-06447475 in Human Nerve-Like Differentiated Cells Exposed to Oxidative Stress Stimuli: Implications for Parkinson's Disease
Miguel Mendivil-Perez et al.
NEUROCHEMICAL RESEARCH (2016)
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers
Kyle B. Fraser et al.
NEUROLOGY (2016)
G2385R and I2020T Mutations Increase LRRK2 GTPase Activity
Dong Hwan Ho et al.
BIOMED RESEARCH INTERNATIONAL (2016)
Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease
Katharina E. Rosenbusch et al.
PARKINSONS DISEASE (2016)
Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy
Sangwook Park et al.
PLOS ONE (2016)
mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
Claudia Manzoni et al.
SCIENTIFIC REPORTS (2016)
LRRK2 autophosphorylation enhances its GTPase activity
Zhiyong Liu et al.
FASEB JOURNAL (2016)
LRRK2 inhibitors and their potential in the treatment of Parkinson's disease: current perspectives
Farzaneh Atashrazm et al.
CLINICAL PHARMACOLOGY-ADVANCES AND APPLICATIONS (2016)
Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection
Liting Hang et al.
MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE (2015)
Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy
Yu-Chin Su et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration
Joao P. L. Daher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes
Bjorn D. M. Bean et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice
M. Yue et al.
NEUROBIOLOGY OF DISEASE (2015)
Effect of selective LRRK2 kinase inhibition on nonhuman primate lung
Reina N. Fuji et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Macrophage Liver Kinase B1 Interacts with IKKβ and Inhibits Inflammatory Signaling in Response to LPS
Zhaoyu Liu et al.
FASEB JOURNAL (2015)
Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), A Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor
Jaclyn L. Henderson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
A Novel GTP-Binding Inhibitor, FX2149, Attenuates LRRK2 Toxicity in Parkinson's Disease Models
Tianxia Li et al.
PLOS ONE (2015)
MLi-2, a Potent, Selective, and Centrally Active Compound for Exploring the Therapeutic Potential and Safety of LRRK2 Kinase Inhibitions
Matthew J. Fell et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Sphingolipid regulation of ezrin, radixin, and moesin proteins family: Implications for cell dynamics
Mohamad Adada et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)
Genetic, Structural, and Molecular Insights into the Function of Ras of Complex Proteins Domains
Laura Civiero et al.
CHEMISTRY & BIOLOGY (2014)
Leucine-rich repeat kinase 2 inhibitors: a review of recent patents (2011-2013)
Raghava R. Kethiri et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
Functional interaction of Parkinsons disease-associated LRRK2 with members of the dynamin GTPase superfamily
Klodjan Stafa et al.
HUMAN MOLECULAR GENETICS (2014)
Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy
Jason Schapansky et al.
HUMAN MOLECULAR GENETICS (2014)
LRRK2: dropping (kinase) inhibitions and seeking an (immune) response
Adamantios Mamais et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
Nathaniel Weygant et al.
MOLECULAR CANCER (2014)
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
Loukia Parisiadou et al.
NATURE NEUROSCIENCE (2014)
LRRK2 Transport Is Regulated by Its Novel Interacting Partner Rab32
Dieter Waschbuesch et al.
PLOS ONE (2014)
In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2
Renee Vancraenenbroeck et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Interaction of LRRK2 with kinase and GTPase signaling cascades
Joon Y. Boon et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
Maria D. Cirnaru et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Genetic Screening for the LRRK2 R1441C and G2019S Mutations in Parkinsonian Patients from Campania
Anna De Rosa et al.
JOURNAL OF PARKINSONS DISEASE (2014)
Maturation of autophagosomes and endosomes: A key role for Rab7
Juha M. T. Hyttinen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
The development of CNS-active LRRK2 inhibitors using property-directed optimisation
Madeline E. Kavanagh et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
Jose M. Bravo-San Pedro et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Crosstalk between autophagy and proteasome protein degradation systems: possible implications for cancer therapy
Slawomir Wojcik
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2013)
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
Yu-Chin Su et al.
HUMAN MOLECULAR GENETICS (2013)
The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons RELEVANCE TO THE PATHOGENESIS OF PARKINSON DISEASE
Anamitra Ghosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
New Synaptic and Molecular Targets for Neuroprotection in Parkinson's Disease
Paolo Calabresi et al.
MOVEMENT DISORDERS (2013)
Interplay of LRRK2 with chaperone-mediated autophagy
Samantha J. Orenstein et al.
NATURE NEUROSCIENCE (2013)
Sleep disturbances in Parkinson's disease: The contribution of dopamine in REM sleep regulation
Marcelo M. S. Lima
SLEEP MEDICINE REVIEWS (2013)
Small Molecule Kinase Inhibitors for LRRK2 and Their Application to Parkinson's Disease Models
Thomas Kramer et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Role of LRRK2 kinase activity in the pathogenesis of Parkinson's disease
Elisa Greggio
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
A link between LRRK2, autophagy and NAADP-mediated endolysosomal calcium signalling
Patricia Gomez-Suaga et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
The GTPase function of LRRK2
Jean-Marc Taymans
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
GSK2578215A; A potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor
Alastair D. Reith et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Characterization of TAE684 as a potent LRRK2 kinase inhibitor
Jinwei Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
C-Y Chen et al.
CELL DEATH AND DIFFERENTIATION (2012)
Mechanisms of LRRK2-Mediated Neurodegeneration
Elpida Tsika et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2012)
Cognitive dysfunction and depression in Parkinson's disease: what can be learned from rodent models?
Hanna S. Lindgren et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2012)
Leucine-rich repeat kinase 2 inhibitors: a patent review (2006-2011)
Xianming Deng et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2012)
Current understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor design
Soumya Ray et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
Mark W. Dodson et al.
HUMAN MOLECULAR GENETICS (2012)
Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors
Anthony A. Estrada et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein
Jingwen Niu et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Neuroprotective Parkinson Disease Protein DJ-1 in Astrocytes and Neurons
Saurabh Khasnavis et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)
LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein
Daniel F. Marker et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants
Chaodong Wang et al.
PARKINSONISM & RELATED DISORDERS (2012)
Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia
Beomsue Kim et al.
PLOS ONE (2012)
Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers
Laura Civiero et al.
PLOS ONE (2012)
Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease
Byoung Dae Lee et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Brain Penetrant LRRK2 Inhibitor
Hwan Geun Choi et al.
ACS MEDICINAL CHEMISTRY LETTERS (2012)
Parkinsonism Due to Mutations in PINK1, Parkin, and DJ-1 and Oxidative Stress and Mitochondrial Pathways
Mark R. Cookson
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
A new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2
Sheila A. Doggrell
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2011)
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models
Zhaohui Liu et al.
HUMAN MOLECULAR GENETICS (2011)
Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death
Dario C. Angeles et al.
HUMAN MUTATION (2011)
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
Veronique Daniels et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Leucine-Rich Repeat Kinase 2 (LRRK2) Cellular Biology: A Review of Recent Advances in Identifying Physiological Substrates and Cellular Functions
Robert E. Drolet et al.
JOURNAL OF NEUROGENETICS (2011)
A QUICK Screen for Lrrk2 Interaction Partners - Leucine-rich Repeat Kinase 2 is Involved in Actin Cytoskeleton Dynamics
Andrea Meixner et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
Xianming Deng et al.
NATURE CHEMICAL BIOLOGY (2011)
Phenotype in parkinsonian and nonparkinsonian LRRK2 G2019S mutation carriers
C. Marras et al.
NEUROLOGY (2011)
Molecular pathways in sporadic PD
Enza Maria Valente et al.
PARKINSONISM & RELATED DISORDERS (2011)
Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
David Ramonet et al.
PLOS ONE (2011)
Efficient Allele-Specific Targeting of LRRK2 R1441 Mutations Mediated by RNAi
Laura de Ynigo-Mojado et al.
PLOS ONE (2011)
LRRK2 signaling pathways: the key to unlocking neurodegeneration?
Daniell C. Berwick et al.
TRENDS IN CELL BIOLOGY (2011)
Mitophagy: the latest problem for Parkinson's disease
Cristofol Vives-Bauza et al.
TRENDS IN MOLECULAR MEDICINE (2011)
The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity
M. Lichtenberg et al.
CELL DEATH & DISEASE (2011)
Models for LRRK2-Linked Parkinsonism
Tianxia Li et al.
PARKINSONS DISEASE (2011)
Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2
Jason P. Covy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)