4.7 Article

HP1 maintains protein stability of H3K9 methyltransferases and demethylases

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Summary: Growing evidence suggests histone H3 lysine 9 methylation, driven by the SUV family of methyltransferases, plays a critical role in tumorigenesis, with both oncogenic and oncosuppressive effects observed. Dysregulation of these enzymes may lead to alterations in transcriptional programs, impacting cancer development.

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