4.7 Letter

SARS-CoV-2 Omicron emergence urges for reinforced One-Health surveillance

Journal

EMBO MOLECULAR MEDICINE
Volume 14, Issue 3, Pages -

Publisher

WILEY
DOI: 10.15252/emmm.202115558

Keywords

-

Funding

  1. URGENCE COVID-19 fundraising campaign of Institut Pasteur
  2. French Government's Investissement d'Avenir program, Laboratoire d'Excellence Integrative Biology of Emerging Infectious Diseases [ANR-10-LABX-62-IBEID]
  3. Agence Nationale de la Recherche [ANR-20COVI-0028-01]
  4. RECOVER project - European Union's Horizon 2020 research and innovation program [101003589]
  5. INCEPTION program (Investissements d'Avenir) [ANR-16-CONV-0005]

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SARS-CoV-2 Omicron variant has substitutions in the receptor binding domain of the spike protein, indicating its potential to infect rodents. The existence of wild animal reservoirs could facilitate the emergence of new variants with the risk of transmission to humans, and therefore should be closely monitored.
SARS-CoV-2 Omicron harbors substitutions in the receptor binding domain of the spike which strongly suggest its capacity to infect rodents. Wild animal reservoirs could favor the emergence of new variants with risks of spillback to humans and should be closely monitored.

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