Related references
Note: Only part of the references are listed.Repurposing of antipsychotic trifluoperazine for treating brain metastasis, lung metastasis and bone metastasis of melanoma by disrupting autophagy flux
Yong Xia et al.
PHARMACOLOGICAL RESEARCH (2021)
EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours
E. Le Rhun et al.
ANNALS OF ONCOLOGY (2021)
Invasive growth associated with cold-inducible RNA-binding protein expression drives recurrence of surgically resected brain metastases
Matthew Dankner et al.
NEURO-ONCOLOGY (2021)
Vascular co-option in brain metastasis
Pedro Garcia-Gomez et al.
ANGIOGENESIS (2020)
Current multidisciplinary management of brain metastases
Michael J. Moravan et al.
CANCER (2020)
Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
Jose L. Orgaz et al.
CANCER CELL (2020)
Current approaches to the management of brain metastases
John H. Suh et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2020)
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines
Manuel Valiente et al.
CANCER RESEARCH (2020)
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
Barbara Oldrini et al.
NATURE COMMUNICATIONS (2020)
An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient Heterogeneity
Shengwei Jiang et al.
CELL REPORTS MEDICINE (2020)
Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets
Damir Vareslija et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets
Damir Vareslija et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)
HSP90 inhibitor DPB induces autophagy and more effectively apoptosis in A549 cells combined with autophagy inhibitors
YanChun Zhao et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2019)
Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization
Harihar Basnet et al.
ELIFE (2019)
Multiple cancer pathways regulate telomere protection
Leire Bejarano et al.
EMBO MOLECULAR MEDICINE (2019)
Blood Brain Barrier Permeability Prediction Using Machine Learning Techniques: An Update
Deeksha Saxena et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2019)
Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1
Aneliya Antonova et al.
CELL REPORTS (2019)
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment
Erin M. Gibson et al.
CELL (2019)
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Surgery in the Management of Adults With Metastatic Brain Tumors
Brian V. Nahed et al.
NEUROSURGERY (2019)
Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation
Susana Cedres et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Clinical trial design for systemic agents in patients with brain metastases from solid tumours: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group
D. Ross Camidge et al.
LANCET ONCOLOGY (2018)
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization
Ekrem Emrah Er et al.
NATURE CELL BIOLOGY (2018)
STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
Neibla Priego et al.
NATURE MEDICINE (2018)
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
Georgios Vlachogiannis et al.
SCIENCE (2018)
Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation
Susana Cedres et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
Jin-Ku Lee et al.
NATURE GENETICS (2018)
Nextpresso: Next Generation Sequencing Expression Analysis Pipeline
O. Grana et al.
CURRENT BIOINFORMATICS (2018)
PI3K: A master regulator of brain metastasis-promoting macrophages/microglia
Raquel Blazquez et al.
GLIA (2018)
The Evolving Landscape of Brain Metastasis
Manuel Valiente et al.
TRENDS IN CANCER (2018)
Phase II study of buparlisib (BKM120) and trastuzumab in patients with HER2+locally advanced or metastatic breast cancer resistant to trastuzumab-based therapy
B. Pistilli et al.
BREAST CANCER RESEARCH AND TREATMENT (2018)
DAPAR & ProStaR: software to perform statistical analyses in quantitative discovery proteomics
Samuel Wieczorek et al.
BIOINFORMATICS (2017)
DDA1, a novel oncogene, promotes lung cancer progression through regulation of cell cycle
Lin Cheng et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)
The HSP90 chaperone machinery
Florian H. Schopf et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Tumor Microenvironment and Differential Responses to Therapy
Eishu Hirata et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Targeting autophagy in cancer
Jean M. Mulcahy Levy et al.
NATURE REVIEWS CANCER (2017)
UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation
Cheng Du et al.
ONCOTARGET (2016)
Impact of Blood-Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases
Matthias Osswald et al.
CLINICAL CANCER RESEARCH (2016)
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells
Wei He et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
An Autophagic Flux Probe that Releases an Internal Control
Takeshi Kaizuka et al.
MOLECULAR CELL (2016)
Divergent clonal selection dominates medulloblastoma at recurrence
A. Sorana Morrissy et al.
NATURE (2016)
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Qing Chen et al.
NATURE (2016)
Updates in the management of brain metastases
Nils D. Arvold et al.
NEURO-ONCOLOGY (2016)
Response assessment criteria for brain metastases: proposal from the RANO group
Nancy U. Lin et al.
LANCET ONCOLOGY (2015)
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
Hui Gao et al.
NATURE MEDICINE (2015)
Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification
Caroline Mauvezin et al.
NATURE COMMUNICATIONS (2015)
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Priscilla K. Brastianos et al.
CANCER DISCOVERY (2015)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
Masaki Mori et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux
Buddhini Samarasinghe et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis
Manuel Valiente et al.
CELL (2014)
Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment
Elena Garralda et al.
CLINICAL CANCER RESEARCH (2014)
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
Lisa Sevenich et al.
NATURE CELL BIOLOGY (2014)
Three-dimensional organotypic culture: experimental models of mammalian biology and disease
Eliah R. Shamir et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Aryl hydrocarbon receptor ligands in cancer: friend and foe
Iain A. Murray et al.
NATURE REVIEWS CANCER (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Pazopanib Inhibits the Activation of PDGFRβ-Expressing Astrocytes in the Brain Metastatic Microenvironment of Breast Cancer Cells
Brunilde Gril et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group
Nancy U. Lin et al.
LANCET ONCOLOGY (2013)
Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group
Nancy U. Lin et al.
LANCET ONCOLOGY (2013)
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
X. Sui et al.
CELL DEATH & DISEASE (2013)
Xenome-a tool for classifying reads from xenograft samples
Thomas Conway et al.
BIOINFORMATICS (2012)
SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells
Kai-Sheng Liu et al.
CANCER LETTERS (2012)
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
Len Neckers et al.
CLINICAL CANCER RESEARCH (2012)
Multiorgan Metastasis of Human HER-2+ Breast Cancer in Rag2-/-;Il2rg-/- Mice and Treatment with PI3K Inhibitor
Patrizia Nanni et al.
PLOS ONE (2012)
Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis
Eun Sung Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A high content screening assay for identifying lysosomotropic compounds
Sashi Nadanaciva et al.
TOXICOLOGY IN VITRO (2011)
Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group
Patrick Y. Wen et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Targeting the dynamic HSP90 complex in cancer
Jane Trepel et al.
NATURE REVIEWS CANCER (2010)
TopHat: discovering splice junctions with RNA-Seq
Cole Trapnell et al.
BIOINFORMATICS (2009)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
Heat Shock Protein 90 Inhibitor 17-Dimethylaminoethylamino-17-Demethoxygeldanamycin Enhances EphA2+ Tumor Cell Recognition by Specific CD8+ T Cells
Mayumi Kawabe et al.
CANCER RESEARCH (2009)
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
Don X. Nguyen et al.
CELL (2009)
CUDC-305, a Novel Synthetic HSP90 Inhibitor with Unique Pharmacologic Properties for Cancer Therapy
Rudi Bao et al.
CLINICAL CANCER RESEARCH (2009)
Heat Shock Protein-90 Inhibitors Increase MHC Class I-Related Chain A and B Ligand Expression on Multiple Myeloma Cells and Their Ability to Trigger NK Cell Degranulation
Cinzia Fionda et al.
JOURNAL OF IMMUNOLOGY (2009)
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp et al.
LANCET ONCOLOGY (2009)
Genes that mediate breast cancer metastasis to the brain
Paula D. Bos et al.
NATURE (2009)
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Ben Langmead et al.
GENOME BIOLOGY (2009)
Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target
Marielle I. Gallegos Ruiz et al.
PLOS ONE (2008)
HSP90 as a marker of progression in melanoma
M. M. McCarthy et al.
ANNALS OF ONCOLOGY (2008)
High HSP90 expression is associated with decreased survival in breast cancer
Elah Pick et al.
CANCER RESEARCH (2007)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
M Esteller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)