Journal
DYES AND PIGMENTS
Volume 198, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2021.110042
Keywords
Aminoglycoside antibiotics; AIE; Sensors; Neomycin; Colorimetric
Funding
- BRNS [58/14/01/2020-BRNS/37047]
- CSIR, New Delhi
- UGC-FRP
- Council of Scientific & Industrial Research (CSIR) , New Delhi, India [02 (0357) /19/EMR-II]
- CSIR-IICT [IICT/Pubs./2020/366]
Ask authors/readers for more resources
This study demonstrated the highly selective and sensitive detection of aminoglycoside antibiotic neomycin using tetraphenylethene-tetraphosphonic acids for the first time. The detection mechanism relies on electrostatic and hydrogen bonding interactions, with a detection limit of 2.088 x 10-10 M. The TPPE-based sensor system can be used for visual detection of neomycin as thin layer chromatography (TLC) sensor for real world applications.
We demonstrated highly selective and sensitive tetraphenylethene -tetraphosphonic acids for the facile detection of aminoglycoside antibiotic neomycin for the first time. Neomycin was found to effectively induce aggregate formation of (4-(1,2,2-tris(4-phosphonophenyl)vinyl)phenyl)phosphonic acid octasodium salt (TPPE) in aqueous solution. The aggregation-induced emission (AIE) response of TPPE was realized upon addition of neomycin in Milli-Q water at pH 7. The detection mechanism relies on electrostatic and hydrogen bonding interactions. The TPPE-based sensor system exhibited a detection limit 2.088 x 10-10 M of neomycin. Further, we demonstrate use of TPPE system for visual detection of neomycin as thin layer chromatography (TLC) sensor to develop kits for real world applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available