Journal
DRUG DISCOVERY TODAY
Volume 27, Issue 5, Pages 1251-1260Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2022.01.001
Keywords
Nanomedicine; Dendrimers; Veterinary medicine; Foot and mouth disease; Swine fever; Hypothermic circulatory arrest; H9N2 avian influenza
Categories
Funding
- FCT-Fundacao para a Ciencia e a Tecnologia [UIDB/00674/2020, UIDP/00674/2020]
- ARDITI-Agencia Regional para o Desenvolvimento da Investigacao Tecnologia e Inovacao [M1420-01-0145-FEDER-000005-CQM+]
- PRC NSFC-CNRS 2019 [21911530230, 199,675]
- CNRS
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Dendrimers are increasingly important in nanomedicine, not only for treating human diseases, but also in veterinary medicine, representing a new therapeutic approach.
Within the nanoparticle (NP) space, dendrimers are becoming increasingly important in the field of nanomedicine, not only to treat human diseases, but also in veterinary medicine, which represents a new therapeutic approach. Major applications include using dendrimers to tackle highly contagious foot-and-mouth disease virus (FMDV) and swine fever virus (SFV) in pigs, FMDV in cattle, hypothermic circulatory arrest (HCA) in dogs, rabies, and H9N2 avian influenza virus in chickens. As we review here, intramuscular (im) subcutaneous (sc), intravenous (iv), and intraperitoneal (ip) routes of administration can be used for the successful application of dendrimers in animals.
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