Related references
Note: Only part of the references are listed.ER-directed TREX1 limits cGAS activation at micronuclei
Lisa Mohr et al.
MOLECULAR CELL (2021)
Chromothripsis drives the evolution of gene amplification in cancer
Ofer Shoshani et al.
NATURE (2021)
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads
David Porubsky et al.
NATURE BIOTECHNOLOGY (2021)
Spatially resolved single-cell genomics and transcriptomics by imaging
Xiaowei Zhuang
NATURE METHODS (2021)
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
Jeffrey J. Quinn et al.
SCIENCE (2021)
RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress
Xiaofeng A. Su et al.
GENES & DEVELOPMENT (2021)
Structural variant evolution after telomere crisis
Sally M. Dewhurst et al.
NATURE COMMUNICATIONS (2021)
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
Marica Rosaria Ippolito et al.
DEVELOPMENTAL CELL (2021)
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
Devon A. Lukow et al.
DEVELOPMENTAL CELL (2021)
Role of spatial patterns and kinetochore architecture in spindle morphogenesis
Pablo Lara-Gonzalez et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2021)
Structural variation in the sequencing era
Steve S. Ho et al.
NATURE REVIEWS GENETICS (2020)
Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer
Anand Vasudevan et al.
DEVELOPMENTAL CELL (2020)
Pan-cancer analysis of whole genomes
Peter J. Campbell et al.
NATURE (2020)
Patterns of somatic structural variation in human cancer genomes
Yilong Li et al.
NATURE (2020)
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Isidro Cortes-Ciriano et al.
NATURE GENETICS (2020)
Chromosome arm aneuploidies shape tumour evolution and drug response
Ankit Shukla et al.
NATURE COMMUNICATIONS (2020)
Mechanisms generating cancer genome complexity from a single cell division error
Neil T. Umbreit et al.
SCIENCE (2020)
The landscape of chromothripsis across adult cancer types
Natalia Voronina et al.
NATURE COMMUNICATIONS (2020)
Understanding the birth of rupture-prone and irreparable micronuclei
Xihan Guo et al.
CHROMOSOMA (2020)
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs
Kevin Hadi et al.
CELL (2020)
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis
John Maciejowski et al.
NATURE GENETICS (2020)
Human ANKLE1 Is a Nuclease Specific for Branched DNA
Junfang Song et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
DNA Repair Syndromes and Cancer: Insights Into Genetics and Phenotype Patterns
Richa Sharma et al.
FRONTIERS IN PEDIATRICS (2020)
Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements
Peter Ly et al.
NATURE GENETICS (2019)
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
Ana C. F. Bolhaqueiro et al.
NATURE GENETICS (2019)
Aneuploidy drives lethal progression in prostate cancer
Konrad H. Stopsack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
DNA double-strand break repair-pathway choice in somatic mammalian cells
Ralph Scully et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Cytokinesis defects and cancer
Susanne M. A. Lens et al.
NATURE REVIEWS CANCER (2019)
Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations
Ying Wai Chan et al.
NATURE CELL BIOLOGY (2018)
The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations
Francesca Menghi et al.
CANCER CELL (2018)
Genomic and Functional Approaches to Understanding Cancer Aneuploidy
Alison M. Taylor et al.
CANCER CELL (2018)
Chromosomal instability drives metastasis through a cytosolic DNA response
Samuel F. Bakhoum et al.
NATURE (2018)
Genome doubling shapes the evolution and prognosis of advanced cancers
Craig M. Bielski et al.
NATURE GENETICS (2018)
LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis
Ye Hong et al.
NATURE COMMUNICATIONS (2018)
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence
Joana Catarina Macedo et al.
NATURE COMMUNICATIONS (2018)
Whole-genome sequencing analysis of CNV using low-coverage and paired-end strategies is efficient and outperforms array-based CNV analysis
Bo Zhou et al.
JOURNAL OF MEDICAL GENETICS (2018)
Nuclear envelope assembly defects link mitotic errors to chromothripsis
Shiwei Liu et al.
NATURE (2018)
Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma
Blandine Boisselier et al.
Oncotarget (2018)
Whole chromosome loss and associated breakage-fusion-bridge cycles transform mouse tetraploid cells
Rozario Thomas et al.
EMBO JOURNAL (2018)
A patch-based tensor decomposition algorithm for M-FISH image classification
Min Wang et al.
CYTOMETRY PART A (2017)
Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining
Peter Ly et al.
NATURE CELL BIOLOGY (2017)
A world of opportunities with nanopore sequencing
Richard M. Leggett et al.
JOURNAL OF EXPERIMENTAL BOTANY (2017)
The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
Pedro A. Mateos-Gomez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Mapping and phasing of structural variation in patient genomes using nanopore sequencing
Mircea Cretu Stancu et al.
NATURE COMMUNICATIONS (2017)
The helicase domain of Polθ counteracts RPA to promote alt-NHEJ
Pedro A. Mateos-Gomez et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities
Samuel F. Bakhoum et al.
TRENDS IN CANCER (2017)
Replication fork instability and the consequences of fork collisions from rereplication
Jessica L. Alexander et al.
GENES & DEVELOPMENT (2016)
Selective advantage of trisomic human cells cultured in non-standard conditions
Samuel D. Rutledge et al.
SCIENTIFIC REPORTS (2016)
DNA repair, genome stability and cancer: a historical perspective
Penny A. Jeggo et al.
NATURE REVIEWS CANCER (2016)
Chromothripsis and Kataegis Induced by Telomere Crisis
John Maciejowski et al.
CELL (2015)
Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells
Anastasia Y. Kuznetsova et al.
CELL CYCLE (2015)
Unifying the DNA End-processing Roles of the Artemis Nuclease KU-DEPENDENT ARTEMIS RESECTION AT BLUNT DNA ENDS
Howard H. Y. Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
A cell-based model system links chromothripsis with hyperploidy
Balca R. Mardin et al.
MOLECULAR SYSTEMS BIOLOGY (2015)
Stress induced by premature chromatin condensation triggers chromosome shattering and chromothripsis at DNA sites still replicating in micronuclei or multinucleate cells when primary nuclei enter mitosis
Georgia I. Terzoudi et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2015)
Chromothripsis from DNA damage in micronuclei
Cheng-Zhong Zhang et al.
NATURE (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia
Yilong Li et al.
NATURE (2014)
Single cell sequencing reveals low levels of aneuploidy across mammalian tissues
Kristin A. Knouse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells
Lorenzo Costantino et al.
SCIENCE (2014)
The Kinetochore
Iain M. Cheeseman
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution
Sally M. Dewhurst et al.
CANCER DISCOVERY (2014)
Punctuated Evolution of Prostate Cancer Genomes
Sylvan C. Baca et al.
CELL (2013)
Criteria for Inference of Chromothripsis in Cancer Genomes
Jan O. Korbel et al.
CELL (2013)
Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome
Teresa Davoli et al.
CELL (2013)
Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei
Emily M. Hatch et al.
CELL (2013)
Pan-cancer patterns of somatic copy number alteration
Travis I. Zack et al.
NATURE GENETICS (2013)
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
Tobias Rausch et al.
CELL (2012)
Cancer chromosomal instability: therapeutic and diagnostic challenges
Nicholas McGranahan et al.
EMBO REPORTS (2012)
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
Remy Betous et al.
GENES & DEVELOPMENT (2012)
Classification of Multicolor Fluorescence In Situ Hybridization (M-FISH) Images With Sparse Representation
Hongbao Cao et al.
IEEE TRANSACTIONS ON NANOBIOSCIENCE (2012)
Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
Silvia Stingele et al.
MOLECULAR SYSTEMS BIOLOGY (2012)
DNA breaks and chromosome pulverization from errors in mitosis
Karen Crasta et al.
NATURE (2012)
Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration
Colby Chiang et al.
NATURE GENETICS (2012)
Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements
Andrew J. Holland et al.
NATURE MEDICINE (2012)
Causes and consequences of aneuploidy in cancer
David J. Gordon et al.
NATURE REVIEWS GENETICS (2012)
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Philip J. Stephens et al.
CELL (2011)
Chromosome Catastrophes Involve Replication Mechanisms Generating Complex Genomic Rearrangements
Pengfei Liu et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions
Diana Mitter et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2011)
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes
Marie Regairaz et al.
JOURNAL OF CELL BIOLOGY (2011)
Mapping copy number variation by population-scale genome sequencing
Ryan E. Mills et al.
NATURE (2011)
Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations
Aniek Janssen et al.
SCIENCE (2011)
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
Wigard P. Kloosterman et al.
GENOME BIOLOGY (2011)
Mechanisms of Chromosomal Instability
Sarah L. Thompson et al.
CURRENT BIOLOGY (2010)
A window into third-generation sequencing
Eric E. Schadt et al.
HUMAN MOLECULAR GENETICS (2010)
Deregulated Aurora-B induced tetraploidy promotes tumorigenesis
Hao G. Nguyen et al.
FASEB JOURNAL (2009)
Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
Pablo Huertas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A mechanism linking extra centrosomes to chromosomal instability
Neil J. Ganem et al.
NATURE (2009)
A mechanism for chromosome segregation sensing by the NoCut checkpoint
Manuel Mendoza et al.
NATURE CELL BIOLOGY (2009)
The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans
Feng Zhang et al.
NATURE GENETICS (2009)
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
Andrew J. Holland et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity
Albert G. Tsai et al.
CELL (2008)
Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
Bret R. Williams et al.
SCIENCE (2008)
Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays
Johan Staaf et al.
GENOME BIOLOGY (2008)
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
Jennifer A. Lee et al.
CELL (2007)
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
Kai Wang et al.
GENOME RESEARCH (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors
Daniela Cimini et al.
CURRENT BIOLOGY (2006)
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
T Fujiwara et al.
NATURE (2005)
From polyploidy to aneuploidy, genome instability and cancer
Z Storchova et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Hidden Markov models approach to the analysis of array CGH data
J Fridlyand et al.
JOURNAL OF MULTIVARIATE ANALYSIS (2004)
Zero-mode waveguides for single-molecule analysis at high concentrations
MJ Levene et al.
SCIENCE (2003)
Frequent chromosomal translocations induced by DNA double-strand breaks
C Richardson et al.
NATURE (2000)
Share Paper
