Genogeographic clustering to identify cross-species concordance of spatial genetic patterns

Aim While in recent years, there have been considerable advances in discerning spatial genetic patterns within species, the task of identifying common patterns across species is still challenging. Approaches using new data from co-sampled species permit rigorous statistical analysis but are often limited to a small number of species. Meta-analyses of published data can encompass a much broader range of species, but are usually restricted by uneven data properties. There is a need for new approaches that bring greater statistical rigour to meta-analyses and are also able to discern more than a single spatial pattern among species. We propose a new approach for comparative multi-species meta-analyses of published population genetic data that address many existing limitations. Innovation The proposed genogeographic clustering technique takes a three-stage approach: (i) use common genetic metrics to gain location-specific measures across the sampled range of each species; (ii) for each species, determine the spatial genetic pattern by fitting a smooth genogeographic trend curve to the genetic data; and (iii) quantitatively cluster species according to their similarity in spatial pattern. We apply this technique to 21 species of intertidal invertebrate from the New Zealand coastline, to resolve common spatial patterns from disparate profiles of genetic diversity. Main conclusions The genogeographic curves are shown to successfully capture the known spatial patterns within each intertidal species and readily permit statistical comparison of those patterns, regardless of sampling and marker inconsistencies. The species clustering technique is shown to discern groups of species that clearly share spatial patterns within groups but differ significantly among groups. Genogeographic species clustering provides a novel approach to discerning multiple common spatial patterns of diversity among a large number of species. It will permit more rigorous comparative studies from diverse published data and can be easily extended to a wide variety of alternative measures of genetic diversity or divergence.

Automated summary

This study proposes a new method for comparative multi-species meta-analysis of published population genetic data. It uses a genogeographic clustering technique to capture common spatial patterns of genetic diversity among species and enables statistical comparison of these patterns. The method provides a novel approach to discern multiple common spatial patterns and allows for more rigorous comparative studies from diverse published data.