4.5 Article

IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group's Criteria

Journal

DIABETES RESEARCH AND CLINICAL PRACTICE
Volume 183, Issue -, Pages -

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2021.109050

Keywords

Prevalence; Gestational diabetes mellitus; International Diabetes Federation; Diabetes Atlas; Regional differences

Funding

  1. Pfizer-MSD Alliance
  2. Sanofi
  3. Novo Nordisk

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The research used IADPSG criteria to estimate the global and regional prevalence of gestational diabetes mellitus (GDM), finding that low-income countries had higher prevalence rates, with the Middle East and North Africa and Southeast Asia having the highest rates.
Aims: The approaches used to screen and diagnose gestational diabetes mellitus (GDM) vary widely. We generated a comparable estimate of the global and regional prevalence of GDM by International Association of Diabetes in Pregnancy Study Group (IADPSG)'s criteria.Methods: We searched PubMed and other databases and retrieved 57 studies to estimate the prevalence of GDM. Prevalence rate ratios of different diagnostic criteria, screening strategies and age groups, were used to standardize the prevalence of GDM in individual studies included in the analysis. Fixed effects meta-analysis was conducted to estimate standardized pooled prevalence of GDM by IDF regions and World Bank country income groups.Results: The pooled global standardized prevalence of GDM was 14.0% (95% confidence interval: 13.97-14.04%). The regional standardized prevalence of GDM were 7.1% (7.0-7.2%) in North America and Caribbean (NAC), 7.8% (7.2-8.4%) in Europe (EUR), 10.4% (10.1-10.7%) in South America and Central America (SACA), 14.2% (14.0-14.4%) in Africa (AFR), 14.7% (14.7-14.8%) in Western Pacific (WP), 20.8% (20.2-21.4%) in South-East Asia (SEA) and 27.6% (26.9-28.4%) in Middle East and North Africa (MENA). The standardized prevalence of GDM in low-, middle-and high-income countries were 12.7% (11.0-14.6%), 9.2% (9.0-9.3%) and 14.2% (14.1-14.2%), respectively.Conclusions: The highest standardized prevalence of GDM was in MENA and SEA, followed by WP and AFR. Among the three World Bank country income groups, high income coun-tries had the highest standardized prevalence of GDM. The standardized estimates for the prevalence of GDM provide an insight for the global picture of GDM.(c) 2021 Elsevier B.V. All rights reserved.

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