Related references
Note: Only part of the references are listed.Review of the Endocannabinoid System
Hui-Chen Lu et al.
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING (2021)
A life-table analysis of the intrauterine fate of malformed human embryos and fetuses
Kohei Shiota
BIRTH DEFECTS RESEARCH (2021)
Revisiting CB1 cannabinoid receptor detection and the exploration of its interacting partners
Pedro F. Esteban et al.
JOURNAL OF NEUROSCIENCE METHODS (2020)
Mechanistic Insights into the Generation and Transduction of Hedgehog Signaling
Xiaofeng Qi et al.
TRENDS IN BIOCHEMICAL SCIENCES (2020)
Signaling in the primary cilium through the lens of the Hedgehog pathway
Eduardo D. Gigante et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2020)
Mapping cannabis potency in medical and recreational programs in the United States
Mary Catherine Cash et al.
PLOS ONE (2020)
Gene-environment interactions: aligning birth defects research with complex etiology
Tyler G. Beames et al.
DEVELOPMENT (2020)
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
Bandarigoda Nipunika Somatilaka et al.
DEVELOPMENTAL CELL (2020)
Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand
Bradley M. Wierbowski et al.
DEVELOPMENTAL CELL (2020)
Contemporary epidemiology of rising atrial septal defect trends across USA 1991-2016: a combined ecological geospatiotemporal and causal inferential study
Albert Stuart Reece et al.
BMC PEDIATRICS (2020)
Cholesterol access in cellular membranes controls Hedgehog signaling
Arun Radhakrishnan et al.
NATURE CHEMICAL BIOLOGY (2020)
Biochemical mechanisms of vertebrate hedgehog signaling
Jennifer H. Kong et al.
DEVELOPMENT (2019)
Cannabis Teratology Explains Current Patterns of Coloradan Congenital Defects: The Contribution of Increased Cannabinoid Exposure to Rising Teratological Trends
Albert Stuart Reece et al.
CLINICAL PEDIATRICS (2019)
We Are All Developmental Biologists
John B. Wallingford
DEVELOPMENTAL CELL (2019)
Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling
Christiane Kowatsch et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2019)
Establishing neuronal diversity in the spinal cord: a time and a place
Andreas Sagner et al.
DEVELOPMENT (2019)
Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction
Eric W. Fish et al.
SCIENTIFIC REPORTS (2019)
OMIM.org: leveraging knowledge across phenotype-gene relationships
Joanna S. Amberger et al.
NUCLEIC ACIDS RESEARCH (2019)
Modeling the complex etiology of holoprosencephaly in mice
Mingi Hong et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2018)
Recent advances in understanding inheritance of holoprosencephaly
Christele Dubourg et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2018)
Holoprosencephaly in the genomics era
Erich Roessler et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2018)
Structural Basis of Smoothened Activation in Hedgehog Signaling
Pengxiang Huang et al.
CELL (2018)
Primary Cilia and Mammalian Hedgehog Signaling
Fiona Bangs et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Gene-environment interactions in development and disease
C. Lovely et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2017)
Cannabinoid receptor 1/2 double-knockout mice develop epilepsy
Shane Rowley et al.
EPILEPSIA (2017)
Trends in Self-reported and Biochemically Tested Marijuana Use Among Pregnant Females in California From 2009-2016
Kelly C. Young-Wolff et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
The Risks of Marijuana Use During Pregnancy
Nora D. Volkow et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition
Antonia Sophocleous et al.
AGING CELL (2017)
Sonic Hedgehog Signaling in Limb Development
Cheryll Tickle et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling
Pengxiang Huang et al.
CELL (2016)
Dose-dependent teratogenicity of the synthetic cannabinoid CP-55,940 in mice
Marcoita T. Gilbert et al.
NEUROTOXICOLOGY AND TERATOLOGY (2016)
Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols
Navdar Sever et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis
J. K. L. Gunn et al.
BMJ OPEN (2016)
Developments in our understanding of the genetic basis of birth defects
Daniel M. Webber et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2015)
Regulation of the oncoprotein Smoothened by small molecules
Hayley J. Sharpe et al.
NATURE CHEMICAL BIOLOGY (2015)
Endocannabinoids are conserved inhibitors of the Hedgehog pathway
Helena Khaliullina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Endocannabinoid signaling at the periphery: 50 years after THC
Mauro Maccarrone et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Developments in our understanding of the genetic basis of birth defects
Daniel M. Webber et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2015)
Definition of Critical Periods for Hedgehog Pathway Antagonist-Induced Holoprosencephaly, Cleft Lip, and Cleft Palate
Galen W. Heyne et al.
PLOS ONE (2015)
Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans
Anna Petryk et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2015)
The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling
Saikat Mukhopadhyay et al.
CELL (2013)
Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification
Jean B. Regard et al.
NATURE MEDICINE (2013)
Cannabinoid Receptor 1 Signaling in Embryo Neurodevelopment
Delphine Psychoyos et al.
BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY (2012)
Utilizing prospective sequence analysis of SHH, ZIC2, SIX3 and TGIF in holoprosencephaly probands to describe the parameters limiting the observed frequency of mutant gene x gene interactions
Erich Roessler et al.
MOLECULAR GENETICS AND METABOLISM (2012)
Cdon Mutation and Fetal Ethanol Exposure Synergize to Produce Midline Signaling Defects and Holoprosencephaly Spectrum Disorders in Mice
Mingi Hong et al.
PLOS GENETICS (2012)
Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation
Luisa Izzi et al.
DEVELOPMENTAL CELL (2011)
Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function
Benjamin L. Allen et al.
DEVELOPMENTAL CELL (2011)
Boc modifies the holoprosencephaly spectrum of Cdo mutant mice
Wei Zhang et al.
DISEASE MODELS & MECHANISMS (2011)
Risk Factors for Non-Syndromic Holoprosencephaly in the National Birth Defects Prevention Study
Eric A. Miller et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2010)
Early Pathogenesis of Holoprosencephaly
Kohei Shiota et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2010)
O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation
Jianguang Du et al.
DEVELOPMENTAL BIOLOGY (2010)
Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study
Marleen M. H. J. van Gelder et al.
DRUG AND ALCOHOL DEPENDENCE (2010)
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube
Vanessa Ribes et al.
GENES & DEVELOPMENT (2010)
Hedgehog Signaling Is Critical for Normal Liver Regeneration After Partial Hepatectomy in Mice
Begona Ochoa et al.
HEPATOLOGY (2010)
Maternal Periconceptional Illicit Drug Use and the Risk of Congenital Malformations
Marleen M. H. J. van Gelder et al.
EPIDEMIOLOGY (2009)
Smoothened Adopts Multiple Active and Inactive Conformations Capable of Trafficking to the Primary Cilium
Christopher W. Wilson et al.
PLOS ONE (2009)
Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
Rajat Rohatgi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Nrf2-mediated transcriptional induction of antioxidant response in mouse embryos exposed to ethanol in vivo:: Implications for the prevention of fetal alcohol spectrum disorders
Jian Dong et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Frequency of holoprosencephaly in the International Clearinghouse Birth Defects Surveillance systems:: Searching for population variations
Emanuele Leoncini et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2008)
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network
Eric Dessaud et al.
DEVELOPMENT (2008)
Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
Aniko Ludanyi et al.
JOURNAL OF NEUROSCIENCE (2008)
The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation
Sheona Watson et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning
Jan Mulder et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo
Yuzhen Zhang et al.
DEVELOPMENT (2007)
Induction of Krox-24 by endogenous cannabinoid type 1 receptors in Neuro2a cells is mediated by the MEK-ERK MAPK pathway and is suppressed by the phosphatidylinositol 3-kinase pathway
E. Scott Graham et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The cell surface membrane proteins cdo and bloc are components and targets of the hedgehog signaling pathway and feedback network in mice
Toyoaki Tenzen et al.
DEVELOPMENTAL CELL (2006)
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
J Svärd et al.
DEVELOPMENTAL CELL (2006)
Holoprosencephaly: Clinical, anatomic, and molecular dimensions
M. Michael Cohen
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2006)
The Gαo/i-coupled cannabinoid receptor-mediated neurite outgrowth involves rap regulation of Src and Stat3
JCJ He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Hedgehog signaling and congenital malformations
E Nieuwenhuis et al.
CLINICAL GENETICS (2005)
Microform holoprosencephaly in mice that lack the Ig superfamily member Cdon
F Cole et al.
CURRENT BIOLOGY (2003)
Pharmacokinetics and pharmacodynamics of cannabinoids
F Grotenhermen
CLINICAL PHARMACOKINETICS (2003)
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen et al.
GENES & DEVELOPMENT (2002)
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
J Taipale et al.
NATURE (2000)