High Flow Nasal Cannula Oxygenation Successfully Used as Bridge Therapy for Systemic Thrombolysis in COVID-19 Associated Intermediate-high Risk Pulmonary Embolism

Review Critical Care Medicine

A Rationale for Use of High Flow Nasal Cannula for Select Patients With Suspected or Confirmed Severe Acute Respiratory Syndrome Coronavirus-2 Infection

Dante A. Suffredini et al.

Summary: Infection with SARS-CoV-2 can lead to severe hypoxemia and respiratory failure, requiring mechanical ventilation in some cases. The use of HFNC in SARS-CoV-2 patients is not well-described, but previous evidence suggests it may be low risk and effective for select patients. Identifying patients who may benefit from HFNC could help allocate ventilators to those who are more critically ill.

JOURNAL OF INTENSIVE CARE MEDICINE (2021)

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Review Medicine, General & Internal

Impact and role of pulmonary embolism response teams in venous thromboembolism associated with COVID-19

Mateo Porres-Aguilar et al.

Summary: Venous thromboembolism associated with COVID-19, especially acute pulmonary embolism, poses challenges in clinical management. Establishing a multidisciplinary pulmonary embolism response team (PERT) can play a crucial role in providing fast, appropriate, team-based care for these patients.

JOURNAL OF INVESTIGATIVE MEDICINE (2021)

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Review Medicine, General & Internal

Submassive Pulmonary Embolism: Current Perspectives and Future Directions

Phillip C. Nguyen et al.

Summary: Patients with submassive pulmonary embolism (PE) have worse outcomes than those with standard-risk PE, and the use of systemic thrombolytic therapy in submassive PE has not shown clear benefits. Interest remains in optimizing thrombolysis, with new therapies in preclinical and early clinical trials being investigated.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Acute pulmonary embolism and systemic thrombolysis in the era of COVID-19 global pandemic 2020: a case series of seven patients admitted to a regional hospital in the French epidemic cluster

John Philippe et al.

Summary: Systemic thrombolysis may be an effective treatment for pulmonary embolism with right ventricular failure in COVID-19 patients, particularly those suffering from ARDS without cardiogenic shock.

EUROPEAN HEART JOURNAL-CASE REPORTS (2021)

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Review Hematology