A Bibliometric Analysis of Familial Hypercholesterolemia From 2011 to 2021

Familial Hypercholesterolemia (FH), an autosomal dominant genetic disease, is increasingly emerging as a global threat. To learn more about the development of FH, 1 617 papers about FH and related research were retrieved in the Web of Science Core Collection from 2011 to 2021. Then, these publications were scientometrically analyzed based on CiteSpace and VOSviewer in terms of spatiotemporal distribu-tion, author distribution, subject categories, topic dis-tribution, and references. The results showed that research on FH is at a stable stage. More FH research has been conducted in developed countries, implying the necessity for strengthening international coopera-tion and exchanges. We have obtained scholars, insti-tutions, relevant journals, and representative literatures that play an important role in FH. The research direction of FH is on the mechanisms of FH and its complications, diagnosis, statin therapy, and new lipid-lowering drug therapy. Care is the research frontier in FH, and it is in an explosive period. (Curr Probl Cardiol 2023;48:101151.)

Automated summary

In this study, 1617 papers on FH and related research from 2011 to 2021 were retrieved and analyzed. The results showed that FH research is at a stable stage and more research has been conducted in developed countries, highlighting the need for strengthening international cooperation and exchanges. The research direction focuses on the mechanisms, complications, diagnosis, statin therapy, and new lipid-lowering drug therapy of FH.