Journal
CURRENT OPINION IN PHARMACOLOGY
Volume 62, Issue -, Pages 152-158Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2021.12.006
Keywords
SARS-CoV-2; Testing strategies; RT-PCR; Antigenic test
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Funding
- ANII (Agencia Nacional de Investigacion e Innovacion, Uruguay)
- FOCEM (MERCOSUR Structural Convergence Fund) [COF 03/11]
- Fondo de Solidaridad para Proyectos Innovadores, Sociedad Civil, Francofonia y Desarrollo Humano (FSPI), Embassy of France
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The article discusses the interpretation and combination of molecular or antigen-based detection methods for SARS-CoV-2, as well as their appropriate usage in different epidemiological contexts.
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has hit every corner of the world faster than any infectious disease ever known. In this context, rapid and accurate testing of positive cases are essential to follow the test-trace-isolate strategy (TETRIS), which has proven to be a key approach to constrain viral spread. Here, we discuss how to interpret and combine molecular or/and antigen-based detection methods for SARS-CoV-2 as well as when they should be used. Their application can be cleverly designed as an algorithm to prevent viral dissemination according to distinct epidemiological contexts within surveillance programs.
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