☆ 4.4 Review

Childhood-onset Takayasu arteritis

CURRENT OPINION IN PEDIATRICS (2022)

Related references

Note: Only part of the references are listed.

Article Genetics & Heredity

Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study

Lourdes Ortiz-Fernandez et al.

Summary: A genetic study on Takayasu arteritis identified HLA risk factors and several susceptibility loci, shedding light on potential disease mechanisms. Comparison to other traits revealed genetic relatedness to inflammatory bowel disease, with epigenetic patterns suggesting roles for monocytes and B cells in Takayasu arteritis.

AMERICAN JOURNAL OF HUMAN GENETICS (2021)

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Article Clinical Neurology

Neuroimaging of Children With Takayasu Arteritis

Hafize Emine Sonmez et al.

Summary: In this study of 15 pediatric Takayasu arteritis patients, all presented with constitutional symptoms. Among those who underwent cranial and diffusion MRI, abnormal findings were observed in 3 patients, including stenosis in cerebral arteries and areas of gliosis. This suggests the importance of careful evaluation of neurologic involvement in all pediatric Takayasu arteritis patients.

JOURNAL OF CHILD NEUROLOGY (2021)

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Review Rheumatology

Wind of Change in the Treatment of Childhood-Onset Takayasu Arteritis: a Systematic Review

Seher Sener et al.

Summary: This review highlights the lack of evidence-based data for treating childhood-onset Takayasu arteritis (c-TA) due to its rarity in children. The review found that steroids are the main immunosuppressive therapy for c-TA patients, with other immunosuppressive agents and biologics being increasingly used in treatment protocols.

CURRENT RHEUMATOLOGY REPORTS (2021)

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Clinical course of 602 patients with Takayasu's arteritis: comparison between Childhood-onset versus adult onset disease

Debashish Danda et al.

Summary: The clinical profile of Asian Indian patients with Takayasu's arteritis showed differences between childhood-onset and adult-onset cases, with childhood-onset patients more likely to have arterial involvement below the diaphragm and higher levels of systemic inflammation, leading to a greater likelihood of achieving remission.

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PRESSE MEDICALE (2017)

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Childhood Takayasu arteritis: disease course and response to therapy

Florence A. Aeschlimann et al.

ARTHRITIS RESEARCH & THERAPY (2017)

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ARTHRITIS RESEARCH & THERAPY (2015)

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EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria

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Juergen Brunner et al.

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Renal manifestations in toddlers with Takayasu's arteritis and malignant hypertension

Rana Hijazi et al.

PEDIATRIC NEPHROLOGY (2009)

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F Numano

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