Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 72, Issue -, Pages 110-117Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2021.11.006
Keywords
-
Categories
Funding
- Wellcome [Awards105031/C/14/Z, 108438/Z/15/Z, 215116/Z/18/Z, 103788/Z/14/Z]
- Wellcome Trust [103788/Z/14/Z, 108438/Z/15/Z, 215116/Z/18/Z] Funding Source: Wellcome Trust
Ask authors/readers for more resources
In this review, the authors focus on the dynamic processes that emergent epithelial cells undergo during the first seven days of mouse development and speculate on the future understanding of the mechanistic bases for these processes through integrative approaches.
The first epithelia to arise in an organism face the challenge of maintaining the integrity of the newly formed tissue, while exhibiting the behavioral flexibility required for morphogenetic processes to occur effectively. Epithelial cells integrate biochemical and biomechanical cues, both intrinsic and extrinsic, in order to bring about the molecular changes which determine their morphology, behavior and fate. In this review we highlight recent advances in our understanding of the various dynamic processes that the emergent epithelial cells undergo during the first seven days of mouse development and speculate what the future holds in understanding the mechanistic bases for these processes through integrative approaches.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available