The role of cellular active stresses in shaping the zebrafish axis

Tissue remodelling and organ shaping during morphogenesis are products of mechanical forces generated at the cellular level. These cell-scale forces can be coordinated across the tissue via information provided by biochemical and mechanical cues. Such coordination leads to the generation of complex tissue shape during morphogenesis. In this short review, we elaborate the role of cellular active stresses in vertebrate axis morphogenesis, primarily using examples from post gastrulation development of the zebrafish embryo.

Automated summary

Tissue remodelling and organ shaping during morphogenesis are influenced by mechanical forces generated at the cellular level, which can be coordinated through biochemical and mechanical cues across the tissue. This coordination leads to the generation of complex tissue shape during morphogenesis, as demonstrated in vertebrate axis morphogenesis, using examples from post gastrulation development of the zebrafish embryo.