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Cellobiose dehydrogenase in biofuel cells

Journal

CURRENT OPINION IN BIOTECHNOLOGY
Volume 73, Issue -, Pages 205-212

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2021.08.013

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Funding

  1. European Union's Horizon 2020 research and innovation program (ERC Consolidators Grant OXIDISE) [726396]

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Enzymatic biofuel cells use enzymes as catalysts to convert fuel and oxidant into electric energy, with wide applications in powering small electronic devices.
Enzymatic biofuel cells utilize oxidoreductases as highly specific and highly active electrocatalysts to convert a fuel and an oxidant even in complex biological matrices like hydrolysates or physiological fluids into electric energy. The hemoflavoenzyme cellobiose dehydrogenase is investigated as a versatile bioelectrocatalyst for the anode reaction of biofuel cells, because it is robust, converts a range of different carbohydrates, and can transfer electrons to the anode by direct electron transfer or via redox mediators. The versatility of cellobiose dehydrogenase has led to the development of various electrode modifications to create biofuel cells and biosupercapacitors that are capable to power small electronic devices like biosensors and connect them wireless to a receiver.

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