Related references
Note: Only part of the references are listed.Ultraviolet Photodissociation Mass Spectrometry for Analysis of Biological Molecules
Jennifer S. Brodbelt et al.
CHEMICAL REVIEWS (2020)
Antibodies to watch in 2020
Helene Kaplon et al.
MABS (2020)
Advancing Mass Spectrometry Technology in cGMP Environments
Da Ren
TRENDS IN BIOTECHNOLOGY (2020)
An evaluation of instrument types for mass spectrometry-based multi-attribute analysis of biotherapeutics
Zhongqi Zhang et al.
MABS (2020)
Recent advances in capillary electrophoresis-mass spectrometry: Instrumentation, methodology and applications
Alexander Stolz et al.
ELECTROPHORESIS (2019)
Mechanisms of color formation in drug substance and mitigation strategies for the manufacture and storage of therapeutic proteins produced using mammalian cell culture
Cheng Du et al.
PROCESS BIOCHEMISTRY (2019)
Multi-Attribute Method for Quality Control of Therapeutic Proteins
Sarah Rogstad et al.
ANALYTICAL CHEMISTRY (2019)
A novel microchip-based imaged CIEF-MS system for comprehensive characterization and identification of biopharmaceutical charge variants
Scott Mack et al.
ELECTROPHORESIS (2019)
Hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs and therapeutic peptides: A review based on the separation characteristics of the hydrophilic interaction chromatography phases
Tohru Ikegami
JOURNAL OF SEPARATION SCIENCE (2019)
Structure, heterogeneity and developability assessment of therapeutic antibodies
Yingda Xu et al.
MABS (2019)
Evolution of a comprehensive, orthogonal approach to sequence variant analysis for biotherapeutics
T. Jennifer Lin et al.
MABS (2019)
Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses
Madhuresh Sumit et al.
ISCIENCE (2019)
Capillary Isoelectric Focusing-Mass Spectrometry Method for the Separation and Online Characterization of Intact Monoclonal Antibody Charge Variants
Jun Dai et al.
ANALYTICAL CHEMISTRY (2018)
Amino acid misincorporation in recombinant proteins
H. Edward Wong et al.
BIOTECHNOLOGY ADVANCES (2018)
Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab
Neungseon Seo et al.
MABS (2018)
MS-based conformation analysis of recombinant proteins in design, optimization and development of biopharmaceuticals
Devrishi Goswami et al.
METHODS (2018)
Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing
Christopher L. Burcham et al.
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 9 (2018)
Discovery, characterization, and remediation of a C-terminal Fc-extension in proteins expressed in CHO cells
Christopher S. Spahr et al.
MABS (2018)
Charge variant native mass spectrometry benefits mass precision and dynamic range of monoclonal antibody intact mass analysis
Aaron O. Bailey et al.
MABS (2018)
A Retrospective Evaluation of the Use of Mass Spectrometry in FDA Biologics License Applications
Sarah Rogstad et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2017)
Application of a Quantitative LC -MS Multiattribute Method for Monitoring Site-Specific Glycan Heterogeneity on a Monoclonal Antibody Containing Two N-Linked Glycosylation Sites
Tian Wang et al.
ANALYTICAL CHEMISTRY (2017)
Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry
Markus Haberger et al.
MABS (2016)
Investigation of Color in a Fusion Protein Using Advanced Analytical Techniques: Delineating Contributions from Oxidation Products and Process Related Impurities
Hangtian Song et al.
PHARMACEUTICAL RESEARCH (2016)
Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics
Vibha Jawa et al.
AAPS JOURNAL (2016)
Metabolomics Analysis of Soy Hydrolysates for the Identification of Productivity Markers of Mammalian Cells for Manufacturing Therapeutic Proteins
Jason Richardson et al.
BIOTECHNOLOGY PROGRESS (2015)
Metabolic markers associated with high mannose glycan levels of therapeutic recombinant monoclonal antibodies
Sohye Kang et al.
JOURNAL OF BIOTECHNOLOGY (2015)
Chemical Modifications of Therapeutic Proteins Induced by Residual Ethylene Oxide
Louise Chen et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics
Richard S. Rogers et al.
MABS (2015)
Application of mass spectrometry to facilitate advanced process controls of biopharmaceutical manufacture
Yelena Lyubarskaya et al.
PHARMACEUTICAL BIOPROCESSING (2015)
Characterization of the Degradation Products of a Color-Changed Monoclonal Antibody: Tryptophan-Derived Chromophores
Yiming Li et al.
ANALYTICAL CHEMISTRY (2014)
Recombinant Antibody Color Resulting from Advanced Glycation End Product Modifications
Margaret Butko et al.
ANALYTICAL CHEMISTRY (2014)
Cell Line Profiling to Improve Monoclonal Antibody Production
Sohye Kang et al.
BIOTECHNOLOGY AND BIOENGINEERING (2014)
Application of Multi-Omics Techniques for Bioprocess Design and Optimization in Chinese Hamster Ovary Cells
Amy Farrell et al.
JOURNAL OF PROTEOME RESEARCH (2014)
Comprehensive tracking of host cell proteins during monoclonal antibody purifications using mass spectrometry
Qingchun Zhang et al.
MABS (2014)
Red colored IgG4 caused by vitamin B 12 from cell culture media combined with disulfide reduction at harvest
Gayle E. Derfus et al.
MABS (2014)
Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study
Jianlin Xu et al.
PROCESS BIOCHEMISTRY (2014)
G/U and Certain Wobble Position Mismatches as Possible Main Causes of Amino Acid Misincorporations
Zhongqi Zhang et al.
BIOCHEMISTRY (2013)
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome
Nathan E. Lewis et al.
NATURE BIOTECHNOLOGY (2013)
Exploring an Orbitrap Analyzer for the Characterization of Intact Antibodies by Native Mass Spectrometry
Sara Rosati et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Proteomic Analysis of Chinese Hamster Ovary Cells
Deniz Baycin-Hizal et al.
JOURNAL OF PROTEOME RESEARCH (2012)
High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans
Andrew M. Goetze et al.
GLYCOBIOLOGY (2011)
An improved trypsin digestion method minimizes digestion-induced modifications on proteins
Da Ren et al.
ANALYTICAL BIOCHEMISTRY (2009)
Isomerization of a single aspartyl residue of anti-epidermal growth factor receptor immunoglobulin γ2 antibody highlights the role avidity plays in antibody activity
Douglas S. Rehder et al.
BIOCHEMISTRY (2008)
Structural and functional characterization of disulfide isoforms of the human IgG2 subclass
Thomas M. Dillon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics
DS Rehder et al.
JOURNAL OF CHROMATOGRAPHY A (2006)
Advances in protein complex analysis using mass spectrometry
AC Gingras et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
The ABC's (and XYZ's) of peptide sequencing
H Steen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry
JEP Syka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)