4.5 Review

Dietary Insights in Neurological Diseases

Journal

Publisher

SPRINGER
DOI: 10.1007/s11910-021-01143-w

Keywords

Nutrition; Dietary interventions; Neurodegenerative diseases; Stroke; Migraine; Multiple sclerosis; Epilepsy

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Dietary interventions can play a role in the pathophysiology of common neurological disorders, with plant-based, low-fat, high-fiber diets potentially reducing the burden of these diseases. Common neurological disorders share similar pathophysiological mechanisms, and dietary interventions can influence these processes to improve clinical outcomes.
Purpose of Review Dietary interventions may play a role in the pathophysiology of common neurological disorders such as Alzheimer's disease, Parkinson's disease, stroke, migraines, multiple sclerosis, and epilepsy. This article describes the most common and impactful dietary regimens for commonly encountered neurological disorders. Recent Findings Plant-based, low-fat, high-fiber diets, rich in antioxidants and other lifestyle interventions may reduce the burden and disability of common neurological disorders. The ketogenic diet, the diet of choice for the treatment of refractory epilepsy, is such an example. Diverse neurological disorders demonstrate several common pathophysiological mechanisms including increased oxidative stress, neuroinflammation, and disrupted metabolism. Dietary interventions can potentially influence these pathophysiological processes and thus favorably alter clinical outcomes. Adequate dietary choices should be considered as part of a continuum of healthy lifestyle choices.

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