Journal
CURRENT ATHEROSCLEROSIS REPORTS
Volume 24, Issue 3, Pages 143-151Publisher
CURRENT MEDICINE GROUP
DOI: 10.1007/s11883-022-00993-0
Keywords
Wall shear stress; Carotid atherosclerosis; Arterial dilatation; Endothelium
Categories
Funding
- MH CZ - DRO (General University Hospital in Prague - VFN) [00064165]
Ask authors/readers for more resources
Wall shear stress plays a significant role in the development of atherosclerosis and its complications, especially in areas with chronically low oscillating wall shear stress such as outer bifurcation walls and inner walls of arches.
Purpose of Review Wall shear stress describes the mechanical influence of blood flow on the arterial wall. In this review, we discuss the role of the wall shear stress in the development of atherosclerosis and its complications. Recent Findings Areas with chronically low, oscillating wall shear stress are most prone to plaque development and include outer bifurcation walls and inner walls of arches. In some diseases, patients have lower wall shear stress even in straight arterial segments; also, these findings were associated with atherosclerosis. High wall shear stress develops in the distal part (shoulder) of a stenosis and contributes to plaque destabilization. Wall shear stress changes are involved in the development of atherosclerosis. They are not fully understood yet and act in concert with tangential wall stress.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available