Related references
Note: Only part of the references are listed.Redox metabolism for improving whole-cell P450-catalysed terpenoid biosynthesis
Behnaz Nowrouzi et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2022)
Pairing of orthogonal chaperones with a cytochrome P450 enhances terpene synthesis in Saccharomyces cerevisiae
Jae-Eung Kim et al.
BIOTECHNOLOGY JOURNAL (2022)
Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid
Sascha Grobe et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
PCPD: Plant cytochrome P450 database and web-based tools for structural construction and ligand docking
Hui Wang et al.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2021)
Conformational Motion of Ferredoxin Enables Efficient Electron Transfer to Heme in the Full-Length P450TT
Zhanfeng Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Efficient production of oxidized terpenoids via engineering fusion proteins of terpene synthase and cytochrome P450
Xi Wang et al.
METABOLIC ENGINEERING (2021)
A bifunctional enzyme belonging to cytochrome P450 family involved in the O-dealkylation and N-dealkoxymethylation toward chloroacetanilide herbicides in Rhodococcus sp. B2
Hong-ming Liu et al.
MICROBIAL CELL FACTORIES (2021)
Natural products in drug discovery: advances and opportunities
Atanas G. Atanasov et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Exploring the Potential of Cytochrome P450 CYP109B1 Catalyzed Regio-and Stereoselective Steroid Hydroxylation
Xiaodong Zhang et al.
FRONTIERS IN CHEMISTRY (2021)
Identification of novel catabolic genes involved in 17β-estradiol degradation by Novosphingobium sp. ES2-1
Shunyao Li et al.
ENVIRONMENTAL MICROBIOLOGY (2021)
CyProduct: A Software Tool for Accurately Predicting the Byproducts of Human Cytochrome P450 Metabolism
Siyang Tian et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2021)
High-level sustainable production of the characteristic protopanaxatriol-type saponins from Panax species in engineered Saccharomyces cerevisiae
Xiaodong Li et al.
METABOLIC ENGINEERING (2021)
Engineering yeast subcellular compartments for increased production of the lipophilic natural products ginsenosides
Yusong Shi et al.
METABOLIC ENGINEERING (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
Cytochrome P450 enzymes in fungal natural product biosynthesis
Xingwang Zhang et al.
NATURAL PRODUCT REPORTS (2021)
Directed Evolution of P450 Fatty Acid Decarboxylases via High-Throughput Screening towards Improved Catalytic Activity
Huifang Xu et al.
CHEMCATCHEM (2020)
Recombinant production of a hard-to-express membrane-bound cytochrome P450 in different yeasts-Comparison of physiology and productivity
Johanna Hausjell et al.
YEAST (2020)
Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis
Qianwen Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Molecular characterization and overexpression analyses of secologanin synthase to understand the regulation of camptothecin biosynthesis in Nothapodytes nimmoniana (Graham.) Mabb.
Gulzar A. Rather et al.
PROTOPLASMA (2020)
Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino acids)
HyunA Park et al.
BIOTECHNOLOGY ADVANCES (2020)
Identification and circumvention of bottlenecks in CYP21A2-mediated premedrol production using recombinant Escherichia coli
Lisa Koenig et al.
BIOTECHNOLOGY AND BIOENGINEERING (2020)
Indigo Formation and Rapid NADPH Consumption Provide Robust Prediction of Raspberry Ketone Synthesis by Engineered Cytochrome P450 BM3
Olivier Rousseau et al.
CHEMCATCHEM (2020)
Functional characterization of cytochrome P450 CYP81A subfamily to disclose the pattern of cross-resistance in Echinochloa phyllopogon
Nina Gracel Dimaano et al.
PLANT MOLECULAR BIOLOGY (2020)
Microbial Chassis Development for Natural Product Biosynthesis
Xianhao Xu et al.
TRENDS IN BIOTECHNOLOGY (2020)
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
Lichan Tu et al.
NATURE COMMUNICATIONS (2020)
Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants
Aitao Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Synthetic Derivatives of (+)-epi-α-Bisabolol Are Formed by Mammalian Cytochromes P450 Expressed in a Yeast Reconstituted Pathway
Arthur Sarrade-Loucheur et al.
ACS SYNTHETIC BIOLOGY (2020)
α, ω-Oxyfunctionalization of C12 alkanes via whole-cell biocatalysis of CYP153A from Marinobacter aquaeolei and a new CYP from Nocardia farcinica IFM10152
Hyun A. Park et al.
BIOCHEMICAL ENGINEERING JOURNAL (2020)
Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids
Lisa Koenig et al.
JOURNAL OF BIOTECHNOLOGY (2020)
Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia
Blake A. Winn et al.
JOURNAL OF NATURAL PRODUCTS (2020)
Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase
Lilan Zhang et al.
NATURE COMMUNICATIONS (2020)
Controlling Chemo- and Regioselectivity of a Plant P450 in Yeast Cell toward Rare Licorice Triterpenoid Biosynthesis
Haijie Xue et al.
ACS CATALYSIS (2020)
Fragrant Venezuelaenes A and B with A 5-5-6-7 Tetracyclic Skeleton: Discovery, Biosynthesis, and Mechanisms of Central Catalysts
Zhong Li et al.
ACS CATALYSIS (2020)
Expression, purification and crystal structure determination of a ferredoxin reductase from the actinobacterium Thermobifida fusca
Jhon Alexander Rodriguez Buitrago et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2020)
Tuning the Binding Affinity of Heme-Responsive Biosensor for Precise and Dynamic Pathway Regulation
Jian Zhang et al.
ISCIENCE (2020)
Metabolic engineering of Saccharomyces cerevisiae for the de novo production of psilocybin and related tryptamine derivatives
N. Milne et al.
METABOLIC ENGINEERING (2020)
Natural Compounds as Pharmaceuticals: The Key Role of Cytochromes P450 Reactivity
Giovanna Di Nardo et al.
TRENDS IN BIOCHEMICAL SCIENCES (2020)
Redox Partners: Function Modulators of Bacterial P450 Enzymes
Shengying Li et al.
TRENDS IN MICROBIOLOGY (2020)
Oxidative Diversification of Steroids by Nature-Inspired Scanning Glycine Mutagenesis of P450BM3 (CYP102A1)
Wenyu Chen et al.
ACS CATALYSIS (2020)
Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK inSchlegelella brevitalea
Junheng Liang et al.
MICROBIAL CELL FACTORIES (2020)
Directed Evolution of a Hydroxylase into a Decarboxylase for Synthesis of 1-Alkenes from Fatty Acids
Shuaibo Wang et al.
ACS CATALYSIS (2020)
Discovery and modification of cytochrome P450 for plant natural products biosynthesis
Xiaonan Liu et al.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2020)
Advanced 96-microtiter plate based bioelectrochemical platform reveals molecular short cut of electron flow in cytochrome P450 enzyme
Ronny Frank et al.
LAB ON A CHIP (2020)
Cytochrome P450 Monooxygenases in Biotechnology and Synthetic Biology
Vlada B. Urlacher et al.
TRENDS IN BIOTECHNOLOGY (2019)
Engineering the Biosynthesis of Caffeic Acid in Saccharomyces cerevisiae with Heterologous Enzyme Combinations
Lanqing Liu et al.
ENGINEERING (2019)
Multi-Functional Oxidase Activity of CYP102A1 (P450BM3) in the Oxidation of Quinolines and Tetrahydroquinolines
Yushu Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
Efficient production of glycyrrhetinic acid in metabolically engineered Saccharomyces cerevisiae via an integrated strategy
Caixia Wang et al.
MICROBIAL CELL FACTORIES (2019)
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
Kai Blin et al.
NUCLEIC ACIDS RESEARCH (2019)
Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production
Hannah Hodgson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
New tools for recombinant protein production in Escherichia coli: A 5-year update
German L. Rosano et al.
PROTEIN SCIENCE (2019)
Efficient biosynthesis of antitumor ganoderic acid HLDOA using a dual tunable system for optimizing the expression of CYP5150L8 and a Ganoderma P450 reductase
Xiaoting Lan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2019)
Hydroxylation of Steroids by a Microbial Substrate-Promiscuous P450 Cytochrome (CYP105D7): Key Arginine Residues for Rational Design
Bingbing Ma et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)
Production of 14α-hydroxysteroids by a recombinant Saccharomyces cerevisiae biocatalyst expressing of a fungal steroid 14α-hydroxylation system
Jing Chen et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)
Integration of a multi-step heterologous pathway in Saccharomyces cerevisiae for the production of abscisic acid
Maximilian Otto et al.
MICROBIAL CELL FACTORIES (2019)
A 96-multiplex capillary electrophoresis screening platform for product based evolution of P450 BM3
Anna Gaertner et al.
SCIENTIFIC REPORTS (2019)
Pregnenolone Overproduction in Yarrowia lipolytica by Integrative Components Pairing of the Cytochrome P450scc System
Ruosi Zhang et al.
ACS SYNTHETIC BIOLOGY (2019)
Chemo- and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase
Hangyu Zhou et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
CYP109E1 from Bacillus megaterium Acts as a 24-and 25-Hydroxylase for Cholesterol
Natalia Putkaradze et al.
CHEMBIOCHEM (2019)
Glycerol improves heterologous biosynthesis of betulinic acid in engineered Yarrowia lipolytica
Jie Sun et al.
CHEMICAL ENGINEERING SCIENCE (2019)
Novel approach to improve progesterone hydroxylation selectivity by CYP106A2 via rational design of adrenodoxin binding
Tanja Sagadin et al.
FEBS JOURNAL (2019)
Engineering Saccharomyces cerevisiae for production of simvastatin
Carly M. Bond et al.
METABOLIC ENGINEERING (2019)
Identification of a novel cytochrome P450 enzyme that catalyzes the C-2α hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories
Zhubo Dai et al.
METABOLIC ENGINEERING (2019)
Tailoring the Saccharomyces cerevisiae endoplasmic reticulum for functional assembly of terpene synthesis pathway
Jae-Eung Kim et al.
METABOLIC ENGINEERING (2019)
Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency
Pingping Wang et al.
CELL DISCOVERY (2019)
Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence
Kentaro Hori et al.
PLANT AND CELL PHYSIOLOGY (2018)
Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone
Yogan Khatri et al.
ACS CHEMICAL BIOLOGY (2018)
Heterologous biosynthesis of (+)-nootkatone in unconventional yeast Yarrowia lipolytica
Xiaoyan Guo et al.
BIOCHEMICAL ENGINEERING JOURNAL (2018)
Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops
Silvia Castrignano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2018)
Cytochrome P450 diversity in the tree of life
David R. Nelson
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2018)
Biosynthesis of a ganoderic acid in Saccharomyces cerevisiae by expressing a cytochrome P450 gene from Ganoderma lucidum
Wen-Fang Wang et al.
BIOTECHNOLOGY AND BIOENGINEERING (2018)
Heterologous production of levopimaric acid in Saccharomyces cerevisiae
Ting Liu et al.
MICROBIAL CELL FACTORIES (2018)
Codon usage clusters correlation: towards protein solubility prediction in heterologous expression systems in E. coli
Leonardo Pellizza et al.
SCIENTIFIC REPORTS (2018)
A novel regulation mechanism of the T7 RNA polymerase based expression system improves overproduction and folding of membrane proteins
Federica Angius et al.
SCIENTIFIC REPORTS (2018)
A tailor-made, self-sufficient and recyclable monooxygenase catalyst based on coimmobilized cytochrome P450 BM3 and glucose dehydrogenase
Donya Valikhani et al.
BIOTECHNOLOGY AND BIOENGINEERING (2018)
Coexpression of 5-Aminolevulinic Acid Synthase Gene Facilitates Heterologous Production of Thermostable Cytochrome P450, CYP119, in Holo Form in Escherichia coli
Yuki Honda et al.
CHEMBIOCHEM (2018)
Endogenous insertion of non-native metalloporphyrins into human membrane cytochrome P450 enzymes
Rahul Yadav et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids
Wenya Tian et al.
NATURE COMMUNICATIONS (2018)
Mechanisms of Cytochrome P450-Catalyzed Oxidations
F. Peter Guengerich
ACS CATALYSIS (2018)
Simultaneous detection of NADPH consumption and H2O2 production using the Ampliflu™ Red assay for screening of P450 activities and uncoupling
Lisa K. Morlock et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)
Semi-rational engineering of CYP153A35 to enhance omega-hydroxylation activity toward palmitic acid
Eunok Jung et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)
Metabolic engineering of Escherichia coli for secretory production of free haem
Xin Rui Zhao et al.
NATURE CATALYSIS (2018)
P450BM3 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations
Nina Beyer et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE
Sarah Matthews et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids
Philipp Arendt et al.
METABOLIC ENGINEERING (2017)
Multienzyme Biosynthesis of Dihydroartemisinic Acid
Xixian Chen et al.
MOLECULES (2017)
Expansion of chemical space for natural products by uncommon P450 reactions
Xingwang Zhang et al.
NATURAL PRODUCT REPORTS (2017)
Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function
Jeffrey D. Rudolf et al.
NATURAL PRODUCT REPORTS (2017)
One-step purification and immobilization of extracellularly expressed sortase A by magnetic particles to develop a robust and recyclable biocatalyst
Xinrui Zhao et al.
SCIENTIFIC REPORTS (2017)
Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae
Matthew G. McDonald et al.
DRUG METABOLISM AND DISPOSITION (2017)
De-bugging and maximizing plant cytochrome P450 production in Escherichia coli with C-terminal GFP fusions
Ulla Christensen et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Process limitations of a whole-cell P450 catalyzed reaction using a CYP153A-CPR fusion construct expressed in Escherichia coli
M. T. Lundemo et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)
Boosting the hydroxyfatty acid synthesis in Escherichia coli by expression of Bacillus megaterium glucose dehydrogenase
Xiangwei Wang et al.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT (2016)
Process development for oxidations of hydrophobic compounds applying cytochrome P450 monooxygenases in-vitro
Jan Brummund et al.
JOURNAL OF BIOTECHNOLOGY (2016)
Improved NADPH Regeneration for Fungal Cytochrome P450 Monooxygenase by Co-Expressing Bacterial Glucose Dehydrogenase in Resting-Cell Biotransformation of Recombinant Yeast
Hyunwoo Jeon et al.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2016)
An engineered outer membrane pore enables an efficient oxygenation of aromatics and terpenes
Anna Joelle Ruff et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2016)
Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli
Paul Quehl et al.
MICROBIAL CELL FACTORIES (2016)
Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli
Bradley Walters Biggs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Regulation of intracellular heme trafficking revealed by subcellular reporters
Xiaojing Yuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Engineering strategies for the fermentative production of plant alkaloids in yeast
Isis J. Trenchard et al.
METABOLIC ENGINEERING (2015)
Identification of universal selectivity-determining positions in cytochrome P450 monooxygenases by systematic sequence-based literature mining
Lukasz Gricman et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2015)
Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations
Rita Bernhardt et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)
Unusually Broad Substrate Profile of Self-Sufficient Cytochrome P450 Monooxygenase CYP116B4 from Labrenzia aggregata
Yue-Cai Yin et al.
CHEMBIOCHEM (2014)
Unusual Cytochrome P450 Enzymes and Reactions
F. Peter Guengerich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Systematic and searchable classification of cytochrome P450 proteins encoded by fungal and oomycete genomes
Venkatesh Moktali et al.
BMC GENOMICS (2012)
Diversity of P450 enzymes in the biosynthesis of natural products
Larissa M. Podust et al.
NATURAL PRODUCT REPORTS (2012)
Identification and treatment of heme depletion attributed to overexpression of a lineage of evolved P450 monooxygenases
Joshua K. Michener et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Heterologous Expression of Human Cytochromes P450 2D6 and CYP3A4 in Escherichia coli and Their Functional Characterization
Yan Pan et al.
PROTEIN JOURNAL (2011)
Human cytochrome P450 4F11: Heterologous expression in bacteria, purification, and characterization of catalytic function
Zhongmei Tang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
DK Ro et al.
NATURE (2006)
System for the expression of recombinant hemoproteins in Escherichia coli
CL Varnado et al.
PROTEIN EXPRESSION AND PURIFICATION (2004)
Share Paper
