4.8 Review

Fluorescent probes in public health and public safety

Journal

COORDINATION CHEMISTRY REVIEWS
Volume 449, Issue -, Pages -

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2021.214208

Keywords

Fluorescent probe; Sensor; Imaging; Public health; Public safety

Funding

  1. National Natural Science Foundation of China [21705120]
  2. Project of Shandong Province Higher Educational Outstanding Youth Innovation Team [2019KJM008]
  3. Natural Science Foundation of Shandong Province, China [ZR2017LB016]
  4. Project of Shandong Province Higher Educational Science and Technology Program [J17KB074]
  5. Brain Pool Program through the National Research Foundation of Korea (NRF) - Ministry of Science and ICT [2020H1D3A1A02080172]
  6. National Research Foundation of Korea [2018R1A3B1052702, NRF-2019M3E5D1A01068998]
  7. National Research Foundation of Korea [4120200213669] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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With the development of human civilization, the international situation is becoming more diversified and multipolar, attracting increasing attention to public health and safety issues. Developing real-time and sensitive on-site detection technology is crucial for dealing with public safety events. Fluorescent probes are increasingly popular for public safety and public health detection due to their high selectivity, rapid response, and simplicity. This review comprehensively discusses the molecular design approaches of fluorescence probes in the field of public safety and health, highlighting the latest paradigms in analytes detection.
With the development of human civilization, the international situation is becoming more and more diversified and multipolar. Public health and safety issues have attracted increasing attention. To develop in situ, real-time and sensitive on-site detection technology is the key element to deal with public safety events. Fluorescent probes are increasingly used in the detection of public safety and public health due to their high selectivity, rapid response and simplicity. Based on the existing knowledge and our experiences, in this review, we comprehensively discuss the molecular design approaches of fluorescence probes in the field of public safety and health, and highlight the state-of-the-art paradigms in analytes detection, such as various narcotics, food additives, latent fingerprints, explosives and poisons. Moreover, the challenges and issues that need to be addressed in the future and a perspective in this research field are also provided. We hope this Review will give a general guidance and complementary insights for the future development of intelligently designed fluorescent probes, spurring the use in practice. (C) 2021 Elsevier B.V. All rights reserved.

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