Journal
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
Volume 21, Issue 2, Pages 2032-2073Publisher
WILEY
DOI: 10.1111/1541-4337.12858
Keywords
aptasensors; electrochemical; food safety; mycotoxins; optical; photoelectrochemical
Categories
Funding
- National Natural Science Foundation of China [81973474, 81673593]
- S&T Program of Hebei [21344801D]
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Aptasensors, with their strong recognition capacity, simple fabrication, rapid response, high sensitivity, low cost, and easy adaptability for in situ measurement, have great potential in food safety inspection and risk assessment.
Mycotoxin contamination in foods has posed serious threat to public health and raised worldwide concern. The development of simple, rapid, facile, and cost-effective methods for mycotoxin detection is of urgent need. Aptamer-based sensors, abbreviated as aptasensors, with excellent recognition capacity to a wide variety of mycotoxins have attracted ever-increasing interest of researchers because of their simple fabrication, rapid response, high sensitivity, low cost, and easy adaptability for in situ measurement. The past few decades have witnessed the rapid advances of aptasensors formycotoxin detection in foods. Therefore, this review first summarizes the reported aptamer sequences specific for mycotoxins. Then, the recent 5-year advancements in various newly developed aptasensors, which, according to the signal outputmode, are divided into electrochemical, optical and photoelectrochemical categories, for mycotoxin detection are comprehensively discussed. A special attention is taken on their strengths and limitations in real-world application. Finally, the current challenges and future perspectives for developing novel highly reliable aptasensors for mycotoxin detection are highlighted, which is expected to provide powerful references for their thorough research and extended applications. Owing to their unique advantages, aptasensors display a fascinating prospect in food field for safety inspection and risk assessment.
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