4.7 Article

Mixed micelles and bicontinuous microemulsions: Promising media for enzymatic reactions

Journal

COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 209, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.colsurfb.2021.112193

Keywords

Enzyme; Novel reaction medium; Mixed micelle; Bicontinuous microemulsion; Surfactant; Ionic liquid

Ask authors/readers for more resources

Enzymes play crucial roles in catalysis, and various reaction media show diverse impacts on enzyme catalysis. Novel media like mixed micelles and bicontinuous microemulsions have the potential to enhance the catalytic efficiency of enzymes.
Enzymes, the natural catalysts, replace catalysts of chemical origin in a wide spectrum of reactions and generally work under environment friendly conditions. Various strategies are adopted to modify catalytic activities of enzymes further, of which one is application of novel reaction medium. This work reviews applicability of novel media like mixed micelles and bicontinuous microemulsions in enzymatic reactions and points out their capa-bility to play bigger roles in enzyme catalysis. Ionic reverse micelles reduced catalytic activities of enzymes through denaturation. Addition of nonionic surfactant to these reverse micelles led to corresponding mixed micelles and thus restored or sometimes enhanced catalytic abilities of enzymes. Mixed micelles comprising of two nonionic surfactants, bicontinuous microemulsion containing two anionic surfactants also acted as efficient reaction media for enzymes. Even a cationic/anionic/nonionic mixed micelle was found to increase activity of enzyme. Mixed micelles and bicontinuous microemulsions comprising of anionic and zwitterionic surfactants augmented enzyme catalysis. Mixed micelles and bicontinuous microemulsions containing ionic liquid and surfactant also had critical impact on enzyme catalysis. Catalytic abilities of enzymes altered significantly in substrate/surfactant and bile salt/surfactant mixed micelles. Concentrations of individual surfactant, molar ratio of surfactants, and molar ratio of water to total surfactants had notable impacts on enzyme catalysis in those media.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available