4.7 Article

Tantalum and its derivatives in orthopedic and dental implants: Osteogenesis and antibacterial properties

Journal

COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 208, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.colsurfb.2021.112055

Keywords

Tantalum; Porous tantalum; Osteogenesis; Antibacterial performances; Surface treatments

Funding

  1. National Natural Science Foundation of China [82071164, 81970984]
  2. Key research program of Sichuan Science and technology Department [2021YFS0052]

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Tantalum and its derivatives have shown significant potential in orthopedic and dental implant applications due to their corrosion resistance, biocompatibility, osseointegration ability, and antibacterial properties. Research focuses on enhancing their osseointegration and antibacterial properties, and various surface modification methods have been summarized.
Implant-associated infections and aseptic loosening are some of the main reasons for implant failure. Therefore, there is an urgent need to improve the osseointegration and antibacterial capabilities of implant materials. In recent years, a large number of breakthroughs in the biological application of tantalum and its derivatives have been achieved. Owing to their corrosion resistance, biocompatibility, osseointegration ability, and antibacterial properties, they have shown considerable potential in orthopedic and dental implant applications. In this review, we provide the latest progress and achievements in the research on osseointegration and antibacterial properties of tantalum as well as its derivatives, and summarize the surface modification methods to enhance their osseointegration and antibacterial properties.

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