Journal
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
Volume 629, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.colsurfa.2021.127489
Keywords
Anodization; Titania nanotubes; Polydopamine; Self-polymerization; Corrosion; MG63 osteoblast-like cells
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Funding
- Science and Engineering Research Board (SERB) , New Delhi, India [SB/S1/PC-14/2013]
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In this study, polydopamine was coated on titania nanotubes (TNTA) to improve corrosion rate and enhance apatite formation, cell adhesion, and proliferation. The surface modification with polydopamine on TNTA shows potential as a promising implant material in bone tissue engineering.
In the present work, polydopamine was coated on titania nanotubes (TNTA) by self-polymerization process. Prior to polydopamine coating, TNTA was sintered at 500 degrees C for 3 h to obtain the anatase/rutile phase. The physicochemical characterization of PDA-TNTA was done by field emission scanning electron microscopy (FE-SEM), attenuated total reflectance fourier transform infrared spectroscopy (ATR-FTIR), UV-Visible spectroscopy and wettability analysis. Polydopamine forms a sheath on the TNTA and diminished the corrosion rate. The high surface-to-volume ratio of PDA-TNTA provided a platform to improve apatite formation, cell adhesion and proliferation. The tailoring of TNTA surface with polydopamine could provide a promising implant material in bone tissue engineering.
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