Related references
Note: Only part of the references are listed.BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Marco H. Hofmann et al.
CANCER DISCOVERY (2021)
KALRN: A central regulator of synaptic function and synaptopathies
Euan Parnell et al.
GENE (2021)
Rho GTPase Signaling in Health and Disease: A Complex Signaling Network
Cord Brakebusch
CELLS (2021)
Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma
Elena A. Afanasyeva et al.
LIFE SCIENCE ALLIANCE (2021)
Induced Pluripotent Stem Cells in Psychiatry: An Overview and Critical
Alejandro De Los Angeles et al.
BIOLOGICAL PSYCHIATRY (2021)
An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank
Stephen M. Smith et al.
NATURE NEUROSCIENCE (2021)
Distinct roles for dopamine clearance mechanisms in regulating behavioral flexibility
Clio Korn et al.
MOLECULAR PSYCHIATRY (2021)
Targeting synaptic plasticity in schizophrenia: insights from genomic studies
Arne W. Mould et al.
TRENDS IN MOLECULAR MEDICINE (2021)
The RHO Family GTPases: Mechanisms of Regulation and Signaling
Niloufar Mosaddeghzadeh et al.
CELLS (2021)
Targeting the Small GTPase Superfamily through Their Regulatory Proteins
Janine L. Gray et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Long-read sequencing reveals the complex splicing profile of the psychiatric risk gene CACNA1C in human brain
Michael B. Clark et al.
MOLECULAR PSYCHIATRY (2020)
Genetics of schizophrenia in the South African Xhosa
S. Gulsuner et al.
SCIENCE (2020)
Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats
Ellis Chika Onwordi et al.
NATURE COMMUNICATIONS (2020)
The small GTPase ARF6 regulates GABAergic synapse development
Hyeonho Kim et al.
MOLECULAR BRAIN (2020)
On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D2/3 receptor agonist radioligand study
Ana Weidenauer et al.
TRANSLATIONAL PSYCHIATRY (2020)
Kalirin and Trio: RhoGEFs in Synaptic Transmission, Plasticity, and Complex Brain Disorders
Jeremiah D. Paskus et al.
TRENDS IN NEUROSCIENCES (2020)
Encoding of contextual fear memory in hippocampal-amygdala circuit
Woong Bin Kim et al.
NATURE COMMUNICATIONS (2020)
Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling
Xiaolong Wang et al.
CELLS (2020)
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions
Paul M. Mueller et al.
NATURE CELL BIOLOGY (2020)
Modeling the complex genetic architectures of brain disease
Michael B. Fernando et al.
NATURE GENETICS (2020)
Opposite regulation of conditioned place preference and intravenous drug self-administration in rodent models: Motivational and non-motivational examples
Thomas A. Green et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2020)
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction
Roman C. Hillig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action
Jeremiah D. Paskus et al.
CELL REPORTS (2019)
A Schizophrenia-Linked KALRN Coding Variant Alters Neuron Morphology, Protein Function, and Transcript Stability
Theron A. Russell et al.
BIOLOGICAL PSYCHIATRY (2018)
Dendritic structural plasticity and neuropsychiatric disease
Marc P. Forrest et al.
NATURE REVIEWS NEUROSCIENCE (2018)
The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival
Hollis McClory et al.
SCIENTIFIC REPORTS (2018)
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
Michael J. Gandal et al.
SCIENCE (2018)
Making Sense of: Sensitization in Schizophrenia
Ana Weidenauer et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2017)
Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity
Megan B. Miller et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors
Taylor P. LaRese et al.
BMC NEUROSCIENCE (2017)
Dendritic Spine Actin Dynamics in Neuronal Maturation and Synaptic Plasticity
Iryna Hlushchenko et al.
CYTOSKELETON (2016)
Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex
Melanie J. Grubisha et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2016)
Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity
Nathan G. Hedrick et al.
NATURE (2016)
Liking, Wanting, and the Incentive-Sensitization Theory of Addiction
Kent C. Berridge et al.
AMERICAN PSYCHOLOGIST (2016)
The Brain's Default Mode Network
Marcus E. Raichle
ANNUAL REVIEW OF NEUROSCIENCE, VOL 38 (2015)
Supervillin Binds the Rac/Rho-GEF Trio and Increases Trio-Mediated Rac1 Activation
Kyonghee Son et al.
CYTOSKELETON (2015)
Approaches of targeting Rho GTPases in cancer drug discovery
Yuan Lin et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses
Jianning Lu et al.
NATURE COMMUNICATIONS (2015)
Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching
Yan Yan et al.
CEREBRAL CORTEX (2015)
A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus
D. -C. Cai et al.
GENES BRAIN AND BEHAVIOR (2014)
Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning
Prashant Mandela et al.
HORMONES AND BEHAVIOR (2014)
Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl
Xin-Ming Ma et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke et al.
NATURE (2014)
Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia
Shashwath A. Meda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness
Theron A. Russell et al.
NATURE COMMUNICATIONS (2014)
Neuregulin1 signaling promotes dendritic spine growth through kalirin
Michael E. Cahill et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Constitutive Knockout of Kalirin-7 Leads to Increased Rates of Cocaine Self-Administration
Drew D. Kiraly et al.
MOLECULAR PHARMACOLOGY (2013)
The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment
Oliver D. Howes et al.
ARCHIVES OF GENERAL PSYCHIATRY (2012)
Abnormalities of the Duo/Ras-Related C3 Botulinum Toxin Substrate 1/p21-Activated Kinase 1 Pathway Drive Myosin Light Chain Phosphorylation in Frontal Cortex in Schizophrenia
Maria D. Rubio et al.
BIOLOGICAL PSYCHIATRY (2012)
Kalrn plays key roles within and outside of the nervous system
Prashant Mandela et al.
BMC NEUROSCIENCE (2012)
Long-term perturbation of spine plasticity results in distinct impairments of cognitive function
Jon-Eric VanLeeuwen et al.
JOURNAL OF NEUROCHEMISTRY (2012)
The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])-MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology
Frank Brand et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: Its role in dendritic pathology
Anthony J. Deo et al.
NEUROBIOLOGY OF DISEASE (2012)
Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility
Itaru Kushima et al.
SCHIZOPHRENIA BULLETIN (2012)
Analysis of Kalirin-7 Knockout Mice Reveals Different Effects in Female Mice
Christopher M. Mazzone et al.
MOLECULAR PHARMACOLOGY (2012)
Genome-Wide Association Study of Schizophrenia in a Japanese Population
Masashi Ikeda et al.
BIOLOGICAL PSYCHIATRY (2011)
Kalrn promoter usage and isoform expression respond to chronic cocaine exposure
Richard E. Mains et al.
BMC NEUROSCIENCE (2011)
Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity
Fouad Lemtiri-Chlieh et al.
BMC NEUROSCIENCE (2011)
Kalirin Binds the NR2B Subunit of the NMDA Receptor, Altering Its Synaptic Localization and Function
Drew D. Kiraly et al.
JOURNAL OF NEUROSCIENCE (2011)
Identification of Kalirin-7 as a Potential Post-Synaptic Density Signaling Hub
Drew D. Kiraly et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Hippocampal phenotypes in kalirin-deficient mice
Zhong Xie et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Local, persistent activation of Rho GTPases during plasticity of single dendritic spines
Hideji Murakoshi et al.
NATURE (2011)
Neocortical excitation/inhibition balance in information processing and social dysfunction
Ofer Yizhar et al.
NATURE (2011)
Behavioral and Morphological Responses to Cocaine Require Kalirin7
Drew D. Kiraly et al.
BIOLOGICAL PSYCHIATRY (2010)
N-methyl-D-aspartate (NMDA) receptor dysfunction or dysregulation: The final common pathway on the road to schizophrenia?
Joshua T. Kantrowitz et al.
BRAIN RESEARCH BULLETIN (2010)
Kalirin loss results in cortical morphological alterations
Zhong Xie et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
Akiko Hayashi-Takagi et al.
NATURE NEUROSCIENCE (2010)
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
David Warde-Farley et al.
NUCLEIC ACIDS RESEARCH (2010)
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory
Ursula Haditsch et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes
Michael E. Cahill et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The Dopamine Hypothesis of Schizophrenia: Version III - The Final Common Pathway
Oliver D. Howes et al.
SCHIZOPHRENIA BULLETIN (2009)
Autonomous functions for the Sec14p/spectrin-repeat region of Kalirin
Martin R. Schiller et al.
EXPERIMENTAL CELL RESEARCH (2008)
Kalirin-7 Is Required for Synaptic Structure and Function
Xin-Ming Ma et al.
JOURNAL OF NEUROSCIENCE (2008)
Synaptic plasticity: Multiple forms, functions, and mechanisms
Ami Citri et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines
Zhong Xie et al.
NEURON (2007)
Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation
Tae Hyeon Koo et al.
BMC CELL BIOLOGY (2007)
The DH and PH domains of trio coordinately engage rho GTPases for their efficient activation
Mariya K. Chhatriwala et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions
Martin R. Schiller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia
J. J. Hill et al.
MOLECULAR PSYCHIATRY (2006)
Synaptic plasticity and dysconnection in schizophrenia
Klaas E. Stephan et al.
BIOLOGICAL PSYCHIATRY (2006)
Critical role for kalirin in nerve growth factor signaling through TrkA
K Chakrabarti et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A direct fluorescence-based assay for RGS domain GTPase accelerating activity
FS Willard et al.
ANALYTICAL BIOCHEMISTRY (2005)
Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: A longitudinal first-episode study with 7-year follow-up
P Milev et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
PJ Harrison et al.
MOLECULAR PSYCHIATRY (2005)
Pathology of layer v pyramidal neurons in the prefrontal cortex of patients with schizophrenia
JE Black et al.
AMERICAN JOURNAL OF PSYCHIATRY (2004)
Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS
MF Green et al.
SCHIZOPHRENIA RESEARCH (2004)
Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: evidence for two forms of spine motility
A Tashiro et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
Genes, dopamine and cortical signal-to-noise ratio in schizophrenia
G Winterer et al.
TRENDS IN NEUROSCIENCES (2004)
Kalirin expression is regulated by multiple promoters
CE McPherson et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Quantification of frontal and temporal lobe brain-imaging findings in schizophrenia: a meta-analysis
LL Davidson et al.
PSYCHIATRY RESEARCH-NEUROIMAGING (2003)
Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
C Pantelis et al.
LANCET (2003)
Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia
PR Szeszko et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Attentional set-shifting in mice:: modification of a rat paradigm, and evidence for strain-dependent variation
G Colacicco et al.
BEHAVIOURAL BRAIN RESEARCH (2002)
Distinct roles for the two Rho GDP/GTP exchange factor domains of kalirin in regulation of neurite growth and neuronal morphology
P Penzes et al.
JOURNAL OF NEUROSCIENCE (2001)
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis
P Penzes et al.
NEURON (2001)
Neuroimaging studies of the hippocampus in schizophrenia
S Heckers
HIPPOCAMPUS (2001)
Regulation of dendritic spine morphology by the Rho family of small GTPases: Antagonistic roles of Rac and Rho
A Tashiro et al.
CEREBRAL CORTEX (2000)
Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons
AY Nakayama et al.
JOURNAL OF NEUROSCIENCE (2000)
Schizophrenia as a disorder of developmentally reduced synaptic connectivity
TH McGlashan et al.
ARCHIVES OF GENERAL PSYCHIATRY (2000)
Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5′- and 3′-ends along with an internal translational initiation site
RC Johnson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
An isoform of Kalirin, a brain-specific GDP/GTP exchange factor, is enriched in the postsynaptic density fraction
P Penzes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
LA Glantz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2000)
Meta-analysis of regional brain volumes in schizophrenia
IC Wright et al.
AMERICAN JOURNAL OF PSYCHIATRY (2000)
Share Paper
