4.7 Review

Prognostic factors for severe and recurrent Clostridioides difficile infection: a systematic review

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

The significance of acute kidney injury in Clostridioides difficile infection

Tomer Avni et al.

Summary: Patients with CDI and AKI have a higher risk of mortality and further deterioration of renal function. Early renal function recovery does not protect against further deterioration of renal function at 3 months. Caution and nephrology follow-up should be considered for all patients who develop AKI during CDI, regardless of discharge creatinine levels.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

Article Gastroenterology & Hepatology

External validation of two prediction tools for patients at risk for recurrent Clostridioides difficile infection

Tessel M. van Rossen et al.

Summary: The study aimed to externally validate clinical prediction tools for recurrent Clostridioides difficile infection, but found poor performance of the selected tools in the validation cohort. The AUC values for Cobo 2018 and Larrainzar-Coghen 2016 prediction tools were 0.43 and 0.42, respectively, indicating that currently identified clinical risk factors may not be sufficient for accurate prediction of rCDI.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2021)

Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Article Geriatrics & Gerontology

Acute Clostridioides difficile Infection in Hospitalized Persons Aged 75 and Older: 30-Day Prognosis and Risk Factors for Mortality

Arnaud Caupenne et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2020)

Article Infectious Diseases

Clostridioides difficile infection in immunocompromised hospitalized patients is associated with a high recurrence rate

Tomer Avni et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Article Gastroenterology & Hepatology

Clostridioides difficile ribotype distribution in a large teaching hospital in Serbia

Milos Korac et al.

GUT PATHOGENS (2020)

Article Geriatrics & Gerontology

Clinical significance of a positive Clostridioides difficile glutamate dehydrogenase test on the outcomes of hospitalized older patients

Yohsuke Nagayoshi et al.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2020)

Article Health Care Sciences & Services

Risk Factors Associated with Recurrent Clostridioides difficile Infection

Nicoleta Negrut et al.

HEALTHCARE (2020)

Article Infectious Diseases

Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes

M. Falcone et al.

CLINICAL MICROBIOLOGY AND INFECTION (2019)

Article Pharmacology & Pharmacy

Predictors of Clostridioides difficile recurrence across a national cohort of veterans in outpatient, acute, and long-term care settings

Haley J. Appaneal et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2019)

Article Multidisciplinary Sciences

Risk factors and treatment outcomes of severe Clostridioides difficile infection in Singapore

H. L. Tay et al.

SCIENTIFIC REPORTS (2019)

Article Public, Environmental & Occupational Health

Risk prediction for 30-day mortality among patients with Clostridium difficile infections: a retrospective cohort study

Hsiu-Yin Chiang et al.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2019)

Article Gastroenterology & Hepatology

Nonsteroidal Anti-Inflammatory Drugs Impact on the Outcomes of Hospitalized Patients with Clostridium difficile Infection

Harish Patel et al.

CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY (2019)

Article Gastroenterology & Hepatology

Clostridium difficile fecal toxin level is associated with disease severity and prognosis

Nathaniel A. Cohen et al.

UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2018)

Review Infectious Diseases

Update of treatment algorithms for Clostridium difficile infection

R. E. Ooijevaar et al.

CLINICAL MICROBIOLOGY AND INFECTION (2018)

Article Infectious Diseases

Host factors are more important in predicting recurrent Clostridium difficile infection than ribotype and use of antibiotics

Y. H. van Beurden et al.

CLINICAL MICROBIOLOGY AND INFECTION (2018)

Meeting Abstract Gastroenterology & Hepatology

RANDOMIZED CLINICAL TRIAL: SINGLE-INFUSION FMT VERSUS MULTIPLE-INFUSION FMT FOR THE TREATMENT OF SEVERE C. DIFFICILE INFECTION

G. Ianiro et al.

DIGESTIVE AND LIVER DISEASE (2018)

Article Infectious Diseases

Risk factors for recurrent Clostridium difficile infection in a tertiary hospital in Israel

Wasef Na'amnih et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2018)

Article Medicine, General & Internal

Clinical outcomes of Clostridium difficile infection according to strain type. A prospective study in medical wards

S. Serafino et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2018)

Article Infectious Diseases

Prediction of recurrent clostridium difficile infection at the bedside: the GEIH-CDI score

Javier Cobo et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2018)

Article Gastroenterology & Hepatology

Acute kidney injury impact on inpatient mortality in Clostridium difficile infection: A national propensity-matched study

Paris Charilaou et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2018)

Article Public, Environmental & Occupational Health

Tobacco use as a screener for Clostridium difficile infection outcomes

A. K. Barker et al.

JOURNAL OF HOSPITAL INFECTION (2018)

Article Cardiac & Cardiovascular Systems

Thrombocytopenia in hospitalized patients with severe clostridium difficile infection

Eric M. Fountain et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2017)

Article Infectious Diseases

Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of C-difficile infection (CDI)?

C. E. Berry et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2017)

Article Public, Environmental & Occupational Health

External Validation of Three Prediction Tools for Patients at Risk of a Complicated Course of Clostridium difficile Infection: Disappointing in an Outbreak Setting

Yvette H. van Beurden et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2017)

Article Medicine, General & Internal

Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection

M. H. Wilcox et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Predictors of 30-Day Mortality in Hospitalized Patients with Clostridium difficile Infection

Jayakrishna Chintanaboina et al.

SOUTHERN MEDICAL JOURNAL (2017)

Article Pharmacology & Pharmacy

Development of a bedside scoring system for predicting a first recurrence of Clostridium difficile-associated diarrhea

Velliyur Viswesh et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2017)

Article Public, Environmental & Occupational Health

Role of binary toxin in the outcome of Clostridium difficile infection in a non-027 ribotype setting

E. Reigadas et al.

EPIDEMIOLOGY AND INFECTION (2016)

Article Medicine, General & Internal

Epidemiology, outcomes, and predictors of mortality in hospitalized adults with Clostridium difficile infection

Sahil Khanna et al.

INTERNAL AND EMERGENCY MEDICINE (2016)

Article Infectious Diseases

The effect of statins on the outcome of Clostridium difficile infection in hospitalized patients

A. Atamna et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2016)

Article Infectious Diseases

First recurrence of Clostridium difficile infection: clinical relevance, risk factors, and prognosis

T. Larrainzar-Coghen et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2016)

Article Pharmacology & Pharmacy

Identification of Factors Impacting Recurrent Clostridium difficile Infection and Development of a Risk Evaluation Tool

Bethanne P. Carpenter et al.

JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2016)

Article Geriatrics & Gerontology

Evaluation of advanced age as a risk factor for severe Clostridium difficile infection

Ursula C. Patel et al.

JOURNAL OF CLINICAL GERONTOLOGY & GERIATRICS (2016)

Article Public, Environmental & Occupational Health

Delirium and other clinical factors with Clostridium difficile infection that predict mortality in hospitalized patients

Laurie R. Archbald-Pannone et al.

AMERICAN JOURNAL OF INFECTION CONTROL (2015)

Article Surgery

Appendectomy: a risk factor for colectomy in patients with Clostridium difficile

Felix A. Yong et al.

AMERICAN JOURNAL OF SURGERY (2015)

Review Infectious Diseases

Emergence of community-acquired Clostridium difficile infection: the experience of a French hospital and review of the literature

Maja Ogielska et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015)

Article Medicine, General & Internal

Burden of Clostridium difficile Infection in the United States

Fernanda C. Lessa et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Continuous Proton Pump Inhibitor Therapy and the Associated Risk of Recurrent Clostridium difficile Infection

Emily G. McDonald et al.

JAMA INTERNAL MEDICINE (2015)

Article Public, Environmental & Occupational Health

Clostridium difficile Infection (CDI) Severity and Outcome among Patients Infected with the NAP1/BI/027 Strain in a Non-Epidemic Setting

T. Scardina et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2015)

Article Medicine, General & Internal

A prediction model for Clostridium difficile recurrence

Francis D. LaBarbera et al.

JOURNAL OF COMMUNITY HOSPITAL INTERNAL MEDICINE PERSPECTIVES (2015)

Article Immunology

NAP1 Strain Type Predicts Outcomes From Clostridium difficile Infection

Isaac See et al.

CLINICAL INFECTIOUS DISEASES (2014)

Article Immunology

Risk Estimation for Recurrent Clostridium difficile Infection Based on Clinical Factors

Ralph B. D'Agostino et al.

CLINICAL INFECTIOUS DISEASES (2014)

Article Infectious Diseases

Predicting a complicated course of Clostridium difficile infection at the bedside

M. P. M. Hensgens et al.

CLINICAL MICROBIOLOGY AND INFECTION (2014)

Article Infectious Diseases

Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality

J. H. Boone et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2014)

Article Infectious Diseases

Severity and frequency of community-onset Clostridium difficile infection on an Australian tertiary referral hospital campus

Penny Clohessy et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2014)

Article Medicine, General & Internal

Development and Validation of a Recurrent Clostridium difficile Risk-Prediction Model

Marya D. Zilberberg et al.

JOURNAL OF HOSPITAL MEDICINE (2014)

Article Critical Care Medicine

Fulminant Clostridium difficile colitis: Prospective development of a risk scoring system

Gwendolyn M. van der Wilden et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2014)

Article Medicine, General & Internal

Severe Clostridium difficile infection: incidence and risk factors at a tertiary care university hospital in Vienna, Austria

Peter Starzengruber et al.

WIENER KLINISCHE WOCHENSCHRIFT (2014)

Article Gastroenterology & Hepatology

Proton Pump Inhibitors and Risk for Recurrent Clostridium difficile Infection Among Inpatients

Daniel E. Freedberg et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2013)

Review Gastroenterology & Hepatology

Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile Infections

Christina M. Surawicz et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2013)

Review Medicine, General & Internal

Assessing Bias in Studies of Prognostic Factors

Jill A. Hayden et al.

ANNALS OF INTERNAL MEDICINE (2013)

Article Gastroenterology & Hepatology

Clinical Factors Associated With Development of Severe-Complicated Clostridium difficile Infection

Raina Shivashankar et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2013)

Article Infectious Diseases

Impact of ribotype 027 on Clostridium difficile infection in a geriatric department

G. Mascart et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2013)

Article Public, Environmental & Occupational Health

Electronic Health Record-Based Detection of Risk Factors for Clostridium difficile Infection Relapse

Courtney Hebert et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2013)

Article Gastroenterology & Hepatology

Acute Kidney Injury is an Independent Marker of Severity in Clostridium difficile Infection: A Nationwide Survey

Sahil Khanna et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2013)

Article Geriatrics & Gerontology

Effect of Age on Treatment Outcomes in Clostridium difficile Infection

Thomas J. Louie et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2013)

Article Geriatrics & Gerontology

Poor Functional Status as a Risk Factor for Severe Clostridium difficile Infection in Hospitalized Older Adults

Krishna Rao et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2013)

Article Medicine, General & Internal

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

Els van Nood et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Medicine, General & Internal

Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework

Anna Huguet et al.

SYSTEMATIC REVIEWS (2013)

Article Gastroenterology & Hepatology

Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease

A. N. Ananthakrishnan et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2012)

Article Gastroenterology & Hepatology

The Epidemiology of Community-Acquired Clostridium difficile Infection: A Population-Based Study

Sahil Khanna et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)

Article Immunology

Clostridium difficile Ribotype Does Not Predict Severe Infection

Seth T. Walk et al.

CLINICAL INFECTIOUS DISEASES (2012)

Article Gastroenterology & Hepatology

PPI Therapy and Albumin are Better Predictors of Recurrent Clostridium difficile Colitis than Choice of Antibiotics

Alizah Rotramel et al.

JOURNAL OF GASTROINTESTINAL SURGERY (2012)

Article Medicine, General & Internal

Gastric Acid Suppression and Outcomes in Clostridium difficile Infection: A Population-Based Study

Sahil Khanna et al.

MAYO CLINIC PROCEEDINGS (2012)

Review Multidisciplinary Sciences

Prediction Tools for Unfavourable Outcomes in Clostridium difficile Infection: A Systematic Review

Claire Nour Abou Chakra et al.

PLOS ONE (2012)

Article Gastroenterology & Hepatology

Risk Factors for Recurrent Clostridium difficile Infection

Han Seung Ryu et al.

INTESTINAL RESEARCH (2012)

Article Public, Environmental & Occupational Health

Diabetes mellitus as a risk factor for recurrence of Clostridium difficile infection in the acute care hospital setting

Rada Shakov et al.

AMERICAN JOURNAL OF INFECTION CONTROL (2011)

Article Medicine, General & Internal

Antimicrobial Use and Risk for Recurrent Clostridium difficile Infection

Dimitri M. Drekonja et al.

AMERICAN JOURNAL OF MEDICINE (2011)

Article Gastroenterology & Hepatology

The Appendix May Protect Against Clostridium difficile Recurrence

Gene Y. Im et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2011)

Article Immunology

Risk Factors Associated With Complications and Mortality in Patients With Clostridium difficile Infection

Rosemary H. Morrison et al.

CLINICAL INFECTIOUS DISEASES (2011)

Article Public, Environmental & Occupational Health

CSI: a severity index for Clostridium difficile infection at the time of admission

O. A. Lungulescu et al.

JOURNAL OF HOSPITAL INFECTION (2011)

Article Public, Environmental & Occupational Health

Co-morbidities as predictors of mortality in Clostridium difficile infection and derivation of the ARC predictive score

M. R. Welfare et al.

JOURNAL OF HOSPITAL INFECTION (2011)

Article Public, Environmental & Occupational Health

High Horn's index score predicts poor outcomes in patients with Clostridium difficile infection

V. Arora et al.

JOURNAL OF HOSPITAL INFECTION (2011)

Article Medicine, General & Internal

Clostridium difficile infection in Europe: a hospital-based survey

Martijn P. Bauer et al.

LANCET (2011)

Article Medicine, General & Internal

Fidaxomicin versus Vancomycin for Clostridium difficile Infection

Thomas J. Louie et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Medicine, General & Internal

Clinical Predictors and Risk Factors for Relapsing Clostridium difficile Infection

Jose Cadena et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2010)

Article Medicine, General & Internal

Proton Pump Inhibitors and Risk for Recurrent Clostridium difficile Infection

Amy Linsky et al.

ARCHIVES OF INTERNAL MEDICINE (2010)

Article Gastroenterology & Hepatology

Mortality and risk stratification in patients with Clostridium difficile-associated diarrhoea

S. Bhangu et al.

COLORECTAL DISEASE (2010)

Article Gastroenterology & Hepatology

C. difficile Colitis-Predictors of Fatal Outcome

Haig Dudukgian et al.

JOURNAL OF GASTROINTESTINAL SURGERY (2010)

Article Surgery

Fulminant Clostridium difficile Colitis Patterns of Care and Predictors of Mortality

Elizabeth A. Sailhamer et al.

ARCHIVES OF SURGERY (2009)

Article Critical Care Medicine

Clostridium difficile-associated disease and mortality among the elderly critically ill

Marya D. Zilberberg et al.

CRITICAL CARE MEDICINE (2009)

Article Immunology

Clinical Risk Factors for Severe Clostridium difficile-associated Disease

Timothy J. Henrich et al.

EMERGING INFECTIOUS DISEASES (2009)

Review Infectious Diseases

Emergence of Clostridium difficile-associated disease in North America and Europe

E. J. Kuijper et al.

CLINICAL MICROBIOLOGY AND INFECTION (2006)

Article Medicine, General & Internal

Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003:: a changing pattern of disease severity

J Pépin et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2004)

Article Gastroenterology & Hepatology

Clostridium difficile-associated diarrhea:: Predictors of severity in patients presenting to the emergency department

CN Andrews et al.

CANADIAN JOURNAL OF GASTROENTEROLOGY (2003)