Related references
Note: Only part of the references are listed.
Article
Medicine, General & Internal
Nicole Wolter et al.
Summary: According to data analysis from South Africa, individuals infected with the omicron variant have a lower likelihood of hospitalization compared to those infected with non-omicron variants. Furthermore, individuals infected with the omicron variant have a lower odds of severe disease compared to individuals infected with the earlier delta variant.
Article
Immunology
Hanjun Zhao et al.
Summary: The Omicron variant of SARS-CoV-2 has distinct virological characteristics compared to the Delta variant. It replicates more slowly and its entry pathway is mediated primarily through the endocytic pathway instead of TMPRSS2 pathway. This difference in entry pathway may have implications for the clinical manifestations or severity of the disease.
EMERGING MICROBES & INFECTIONS
(2022)
Article
Medicine, General & Internal
David N. Fisman et al.
Summary: Research in Ontario, Canada, showed that new variants of concern (VOCs) of SARS-CoV-2 have higher risks of hospitalization, ICU admission, and death compared to non-VOC strains, with the Delta variant showing the most pronounced increase in risk.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2021)
Article
Infectious Diseases
Miguel Martinez-Lacalzada et al.
Summary: A predictive model was developed and validated to identify COVID-19 patients at risk of critical outcomes based on clinical history and examination findings. The PRIORITY model, utilizing easily obtained clinical information, showed high discrimination and generalizability in predicting critical outcomes for COVID-19 patients.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Mathematical & Computational Biology
Richard D. Riley et al.
Summary: External validation is crucial in examining the performance of prediction models, but current studies often face issues with small sample sizes. To address this, determining the minimum sample size needed for a new external validation study with precise estimation calculations is proposed, taking into account calibration, discrimination, and clinical utility measures.
STATISTICS IN MEDICINE
(2021)
Article
Health Care Sciences & Services
Oon Tek Ng et al.
Summary: The study in Singapore focused on quarantine measures for close contacts to determine the risk of Delta variant infection, vaccine efficacy against SARS-CoV-2, and risk factors associated with acquisition and symptomatic disease. Results showed higher risk of infection with the Delta variant for asymptomatic close contacts and significant protection from vaccination against acquisition and symptomatic disease.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2021)
Article
Medicine, General & Internal
Ben van Calster et al.