4.3 Article

VueBox® for quantitative analysis of contrast-enhanced ultrasound in liver tumors

Journal

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
Volume 80, Issue 4, Pages 473-486

Publisher

IOS PRESS
DOI: 10.3233/CH-211261

Keywords

Dynamic contrast-enhanced ultrasound (DCE-US); liver tumors; VueBox (R); perfusion; quantitative

Funding

  1. National Natural Science Foundation of China [82071942]
  2. Clinical Research Plan of SHDC [SHDC2020CR4060]
  3. Shanghai Municipal Science and Technology Medical Guidance Project [18411967200]

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This review summarizes the applications of VueBox (R) in the diagnosis and treatment monitoring of liver tumors. Existing literature provides evidence of its successful use in the characterization and differential diagnosis of liver lesions, as well as monitoring of local ablative therapies and systemic treatment in oncology.
Dynamic contrast-enhanced ultrasound (DCE-US) enables quantification of tumor perfusion. VueBox (R) is a platform independent external software using DICOM cine loops which objectively provides various DCE-US parameters of tumor vascularity. This review summaries its use for diagnosis and treatment monitoring of liver tumors. The existing literature provides evidence on the successful application of Vuebox (R) based DCE-US for characterization and differential diagnosis of focal liver lesions, as well as on its use for monitoring of local ablative therapies and of modern systemic treatment in oncology.

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