4.7 Article

Combination of hepcidin with neutrophil gelatinase-associated lipocalin for prediction of the development of sepsis-induced acute kidney injury

Related references

Note: Only part of the references are listed.
Article Critical Care Medicine

Use of Biomarkers to Identify Acute Kidney Injury to Help Detect Sepsis in Patients With Infection

John A. Kellum et al.

Summary: The study found that in patients with infection but without a clinical diagnosis of sepsis, the urinary (tissue inhibitor of metalloproteinases-2) x (insulin-like growth factor binding protein 7) test could identify acute kidney injury nearly a day before it became apparent by clinical criteria, potentially aiding in the early detection of sepsis.

CRITICAL CARE MEDICINE (2021)

Article Urology & Nephrology

Mortality and serum hepcidin are associated with persistent and transient acute kidney injury in septic patients

Ze-Liang Qiu et al.

Summary: Persistent AKI is associated with increased 60-day mortality compared with transient AKI in septic patients. Serum hepcidin levels measured when AKI was diagnosed have a fair predictive value to predict the occurrence of persistent AKI in septic patients.

CLINICAL NEPHROLOGY (2021)

Review Biochemistry & Molecular Biology

Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis

Elizabeta Nemeth et al.

Summary: Iron regulation in organisms is primarily controlled by the interaction of the iron-regulatory peptide hormone hepcidin and its receptor ferroportin, which plays a crucial role in maintaining iron homeostasis. Dysregulation of hepcidin can lead to iron overload disorders or iron deficiency, affecting iron delivery and compensatory erythropoiesis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Editorial Material Medical Laboratory Technology

Hepcidin-25 as a Novel Kidney Biomarker for Cardiac Surgery-Associated Acute Kidney Injury

Sun Young Cho et al.

ANNALS OF LABORATORY MEDICINE (2021)

Article Medicine, General & Internal

Elevated plasma level of neutrophil gelatinase-associated lipocalin (NGAL) in patients with breast cancer

Ching-Ting Wei et al.

Summary: Plasma NGAL levels were found to be significantly elevated in patients with breast cancer, independently associated with the disease even after adjusting for known biomarkers. The levels were also correlated with disease severity and inflammatory biomarkers, suggesting a potential role of NGAL in breast cancer pathogenesis through inflammatory reactions.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)

Article Endocrinology & Metabolism

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells

Andrew J. Schwartz et al.

Summary: The study reveals that ectopic expression of hepcidin in colorectal cancer plays a critical role in sequestering iron to maintain the nucleotide pool and support cell proliferation. The findings suggest that tumors may modulate local iron handling mechanisms to sustain growth, and deficiency of hepcidin can inhibit tumor development.

NATURE METABOLISM (2021)

Editorial Material Critical Care Medicine

Identifying the Patient at Risk for Acute Kidney Injury: Pediatric Sepsis Biomarker Risk Model Study

Jason Gien et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

Article Medicine, General & Internal

Soluble Urokinase Receptor and Acute Kidney Injury

Salim S. Hayek et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Pharmacology & Pharmacy

Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury

Yogesh Scindia et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Medicine, Research & Experimental

Hepcidin - Potential biomarker of contrast-induced acute kidney injury in patients undergoing percutaneous coronary interventions

Jolanta Malyszko et al.

ADVANCES IN MEDICAL SCIENCES (2019)

Review Urology & Nephrology

Iron Homeostasis in Healthy Kidney and its Role in Acute Kidney Injury

Yogesh Scindia et al.

SEMINARS IN NEPHROLOGY (2019)

Review Medicine, General & Internal

Sepsis associated acute kidney injury

Jason T. Poston et al.

BMJ-BRITISH MEDICAL JOURNAL (2019)

Review Urology & Nephrology

Iron Homeostasis Pathways as Therapeutic Targets in Acute Kidney Injury

Sundararaman Swaminathan

NEPHRON (2018)

Article Medicine, General & Internal

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

Review Urology & Nephrology

Iron metabolism in the pathogenesis of iron-induced kidney injury

A. M. F. Martines et al.

NATURE REVIEWS NEPHROLOGY (2013)

Article Transplantation

Greater increase in urinary hepcidin predicts protection from acute kidney injury after cardiopulmonary bypass

John R. Prowle et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)

Review Multidisciplinary Sciences

Hepcidin and the Iron-Infection Axis

Hal Drakesmith et al.

SCIENCE (2012)

Article Physiology

Urine albumin as a biomarker in acute kidney injury

Subhashini Bolisetty et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)

Review Critical Care Medicine

Urinary hepcidin: an inverse biomarker of acute kidney injury after cardiopulmonary bypass?

John R. Prowle et al.

CURRENT OPINION IN CRITICAL CARE (2010)

Article Urology & Nephrology

Septic acute kidney injury in critically ill patients: Clinical characteristics and outcomes

Sean M. Bagshaw et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

Article Urology & Nephrology

Dual action of neutrophil gelatinase-associated lipocalin

Kai M. Schmidt-Ott et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

Article Biochemistry & Molecular Biology

Expression of neutrophil gelatinase-associated lipocalin regulates epithelial morphogenesis in vitro

JA Gwira et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Endocrinology & Metabolism

The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney

H Kulaksiz et al.

JOURNAL OF ENDOCRINOLOGY (2005)

Article Urology & Nephrology

Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury

J Mishra et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)

Article Biochemistry & Molecular Biology

An iron delivery pathway mediated by a lipocalin

J Yang et al.

MOLECULAR CELL (2002)