Related references
Note: Only part of the references are listed.Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI
Chuan'ai Chen et al.
CELL DEATH & DISEASE (2021)
Cartilage oligomeric matrix protein is an endogenous beta-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury
Yi Fu et al.
CELL RESEARCH (2021)
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice
Latha Muniappan et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)
Mitochondrial Protein Poldip2 (Polymerase Delta Interacting Protein 2) Controls Vascular Smooth Muscle Differentiated Phenotype by O-Linked GlcNAc (N-Acetylglucosamine) Transferase-Dependent Inhibition of a Ubiquitin Proteasome System
Felipe Paredes et al.
CIRCULATION RESEARCH (2020)
S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction
Lihong Pan et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Ngoc Nguyen Lunde et al.
ATHEROSCLEROSIS (2020)
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation
Long Shen et al.
CANCER LETTERS (2020)
Prevention of aortic dissection and aneurysm via an ALDH2-mediated switch in vascular smooth muscle cell phenotype
Kehui Yang et al.
EUROPEAN HEART JOURNAL (2020)
Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis (vol 27, pg 147, 2020)
Takafumi Toyohara et al.
CELL STEM CELL (2020)
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction
Hui Yang et al.
CELL DEATH & DISEASE (2020)
Macrophage-Derived Legumain Promotes Pulmonary Hypertension by Activating the MMP (Matrix Metalloproteinase)-2/TGF (Transforming Growth Factor)-β1 Signaling
Peiyuan Bai et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure
Hu Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms
Marc Clement et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Legumain, an asparaginyl endopeptidase, mediates the effect of M2 macrophages on attenuating renal interstitial fibrosis in obstructive nephropathy
Dekun Wang et al.
KIDNEY INTERNATIONAL (2018)
C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease
Zhi-Hao Wang et al.
NATURE COMMUNICATIONS (2018)
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
Tarik Hadi et al.
NATURE COMMUNICATIONS (2018)
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis
Guillermo de Carcer et al.
NATURE MEDICINE (2017)
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction
Guizhen Zhao et al.
CIRCULATION RESEARCH (2017)
ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype
Renjing Liu et al.
CIRCULATION RESEARCH (2017)
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis
Ngoc Nguyen Lunde et al.
ATHEROSCLEROSIS (2017)
Nestin-expressing vascular wall cells drive development of pulmonary hypertension
Farhan Saboor et al.
EUROPEAN RESPIRATORY JOURNAL (2016)
Structure and function of legumain in health and disease
Elfriede Dall et al.
BIOCHIMIE (2016)
PDE1C Negatively Regulates Growth Factor Receptor Degradation and Promotes VSMC Proliferation
Kimio Satoh et al.
CIRCULATION RESEARCH (2015)
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
Zhentao Zhang et al.
NATURE MEDICINE (2014)
Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment
Ze Liu et al.
NATURE COMMUNICATIONS (2014)
Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation
Elfriede Dall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Epidemiology of thoracic aortic dissection
Scott A. LeMaire et al.
NATURE REVIEWS CARDIOLOGY (2011)
Legumain and cathepsin-L expression in human unstable carotid plaque
K. L. Mattock et al.
ATHEROSCLEROSIS (2010)
The Extracellular Matrix: Not Just Pretty Fibrils
Richard O. Hynes
SCIENCE (2009)
Cathepsin cysteine proteases in cardiovascular disease
Suzanne P. M. Lutgens et al.
FASEB JOURNAL (2007)
Legumain/asparaginyl endopeptidase controls extracellular matrix remodeling through the degradation of fibronectin in mouse renal proximal tubular cells
Yoshikata Morita et al.
FEBS LETTERS (2007)
Targeting tumor-associated macrophages as a novel strategy against breast cancer
Yunping Luo et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Molecular regulation of vascular smooth muscle cell differentiation in development and disease
GK Owens et al.
PHYSIOLOGICAL REVIEWS (2004)
Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice
K Shirahama-Noda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
CP Mack et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
