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Colchicine in Patients With Acute Coronary Syndrome Two-Year Follow-Up of the Australian COPS Randomized Clinical Trial

CIRCULATION (2021)

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Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials

Aernoud T. L. Fiolet et al.

Summary: This meta-analysis indicates that low-dose colchicine reduces the risk of major adverse cardiovascular events, myocardial infarction, stroke, and the need for coronary revascularization in patients with coronary disease. There was no difference in all-cause mortality, with fewer cardiovascular deaths but more non-cardiovascular deaths.

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Article Cardiac & Cardiovascular Systems