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Compartmentalisation of molecular catalysts for nonorthogonal tandem catalysis

Journal

CHEMICAL SOCIETY REVIEWS
Volume 51, Issue 1, Pages 57-70

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cs00530h

Keywords

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Funding

  1. U.S. Department of Energy, Office of Basic Energy Sciences, through Catalysis Science [DE-FG02-03ER15459]

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The development of nonorthogonal tandem catalysis allows for the rapid synthesis of complex products using a combination of arbitrary catalysts. Compartmentalising molecular catalysts is key to overcoming incompatibilities and ensuring efficient reactions. Design principles and future directions in the field emphasize the importance of functional materials for compartmentalisation.
The development of nonorthogonal tandem catalysis enables the use of a combination of arbitrary catalysts to rapidly synthesize complex products in a substainable, efficient, and timely manner. The key is to compartmentalise the molecular catalysts, thereby overcoming inherent incompatibilities between individual catalysts or reaction conditions. This tutorial review analyses the development of the past two decades in the field of nonorthogonal tandem catalysis with an emphasis on compartmentalisation strategies. We highlight design principles of functional materials for compartmentalisation and suggest future directions in the field of nonorthogonal tandem catalysis.

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