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Synthesis of Unsymmetrical Biheteroarenes via Dehydrogenative and Decarboxylative Coupling: a Decade Update

Journal

CHEMICAL RECORD
Volume 22, Issue 4, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.202100288

Keywords

Synthesis of unsymmetric biheteroarene; Cross-Dehydrogenative coupling; Decarboxylative coupling; Biheteroarerene; Heterocyclic compounds

Funding

  1. CSIR, New Delhi [02(0455)/21/EMR-II]

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This article provides an overview of recent research and developments in the synthesis of unsymmetrical biheteroarenes via dehydrogenative and decarboxylative couplings, focusing on literature primarily from 2011 to 2021. The content is subdivided based on the catalysts used in the reactions to simplify understanding for readers.
The design and development of robust and efficient methods for installing one heterocycle with another is endowed as a ubiquitous and powerful synthetic strategy to access complex organic biheterocycles in recent days due to their pervasive applications in medicinal as well as material chemistry. This perspective presents an overview on the recent findings and developments for the synthesis of unsymmetrical biheteroarenes via dehydrogenative and decarboxylative couplings with literature coverage mainly extending from 2011 to 2021. For simplification of the readers, the article has been subcategorized based on the catalysts used in the reactions.

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