Journal
CHEMICAL COMMUNICATIONS
Volume 58, Issue 15, Pages 2568-2571Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc06575k
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Funding
- National Natural Science Foundation of China [22177040, 21472070]
- Social Development Key Project of Jiangsu Province [BE2019632]
- 111 Project [111-2-06]
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A metabolic glycoengineering strategy dependent on beta-Gal was developed for efficient tumor cell-selective surface glycan imaging. Targeted immunotherapy was successfully achieved based on this strategy by utilizing an antibody-recruiting approach.
A beta-Gal-dependent metabolic glycoengineering strategy was developed for tumor cell-selective surface glycan imaging with high efficacy. Combined with an antibody-recruiting strategy, targeted immunotherapy was achieved successfully based on this strategy.
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