Advances in allylic and benzylic C-H bond functionalization enabled by metallaphotoredox catalysis

Metallaphoto-catalysis has been established as a robust platform for efficient construction of a range of chemical bonds. Moreover, transformation of native functionalities such as C(sp(3))-H bonds to produce functional molecules represents one of the most attractive strategies in organic synthesis. Merging two powerful methodologies, metallaphoto-catalyzed benzylic and allylic C(sp(3))-H bond functionalizations provide a series of general and mild approaches for diversification of alkylbenzenes and alkenes.

Automated summary

Metallaphoto-catalysis is an efficient platform for constructing various chemical bonds, with the transformation of native functionalities such as C(sp(3))-H bonds into functional molecules being an attractive strategy in organic synthesis. The merging of two powerful methodologies, metallaphoto-catalyzed benzylic and allylic C(sp(3))-H bond functionalizations, offers general and mild approaches for diversifying alkylbenzenes and alkenes.