Related references
Note: Only part of the references are listed.Dual Kinase Inhibition of EGFR/HER2: Design, Synthesis and Molecular Docking of Thiazolylpyrazolyl-Based Aminoquinoline Derivatives as Anticancer Agents**
Rasha Z. Batran et al.
CHEMISTRYSELECT (2021)
HUNK phosphorylates EGFR to regulate breast cancer metastasis
Carly B. Williams et al.
ONCOGENE (2020)
VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents
Eman Y. Ahmed et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib
Alicja Puszkiel et al.
CLINICAL PHARMACOKINETICS (2019)
Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds
Omaima M. Abdelhafez et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis
Tahia K. Mohamed et al.
BIOORGANIC CHEMISTRY (2019)
Synergistic Effect of α-Solanine and Cisplatin Induces Apoptosis and Enhances Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells
Sherien M. El-Daly et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2019)
The PI3K/AKT/mTOR and CDK4/6 Pathways in Endocrine Resistant HR+/HER2-Metastatic Breast Cancer: Biological Mechanisms and New Treatments
Daniele Presti et al.
CANCERS (2019)
Discovery of new quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors and their anticancer activities - Part 1
Debasis Das et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
Novel sulphonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizers
Aiten M. Soliman et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
In vitro antioxidant activity of thiazolidinone derivatives of 1,3-thiazole and 1,3,4-thiadiazole
Mirjana Djukic et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2018)
Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives
Cleudiomar Inacio Lino et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors
Hany A. M. El-Sherief et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
New thiazolyl-coumarin hybrids: Design, synthesis, characterization, X-ray crystal structure, antibacterial and antiviral evaluation
Hasnah Osman et al.
JOURNAL OF MOLECULAR STRUCTURE (2018)
Dasatinib: A Review in Chronic Myeloid Leukaemia and Ph plus Acute Lymphoblastic Leukaemia
Gillian M. Keating
DRUGS (2017)
LC-MS/MS assay for the quantitation of the tyrosine kinase inhibitor neratinib in human plasma
Brian F. Kiesel et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2017)
Synthesis, Characterization, Crystal Structure and Antimalarial Activity of (2E)-2-(1-{4-[(7-chloroquinolin-4-yl)amino]phenyl}ethylidene)hydrazine Carbothioamide
Yonathan de J. Parra et al.
ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY (2017)
New Coumarin Derivatives as Anti-Breast and Anti-Cervical Cancer Agents Targeting VEGFR-2 and p38 MAPK
Rasha Z. Batran et al.
ARCHIV DER PHARMAZIE (2017)
Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors
Yuanbiao Tu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Study of novel anticancer 4-thiazolidinone derivatives
Konrad A. Szychowski et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2017)
3-Substituted-4-hydroxycoumarin as a new scaffold with potent CDK inhibition and promising anticancer effect: Synthesis, molecular modeling and QSAR studies
Nehad A. Abdel Latif et al.
BIOORGANIC CHEMISTRY (2016)
EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagus
Eva-Maria Birkman et al.
BMC CANCER (2016)
miRs-134 and-370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling
Sherien M. El-Daly et al.
SCIENTIFIC REPORTS (2016)
Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery
Adile Ayati et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Design, synthesis and anticancer activity of furochromone and benzofuran derivatives targeting VEGFR-2 tyrosine kinase
Omaima M. Abdelhafez et al.
RSC ADVANCES (2015)
Novel thiazole derivatives: a patent review (2008-2012. Part 2)
Alberto Leoni et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2014)
Epidermal growth factor receptor mutations in lung adenocarcinoma
Markus D. Siegelin et al.
LABORATORY INVESTIGATION (2014)
New 4-thiazolidinones from 5-ethyl pyridine-2-ethanol: their antibacterial, antifungal, and antitubercular activity
Navin B. Patel et al.
MEDICINAL CHEMISTRY RESEARCH (2014)
Characterization of EGFR family gene aberrations in cholangiocarcinoma
Xiaoqing Yang et al.
ONCOLOGY REPORTS (2014)
Design, synthesis and anticancer activity of benzofuran derivatives targeting VEGFR-2 tyrosine kinase
Omaima M. Abdelhafez et al.
RSC ADVANCES (2014)
Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl)amino]chalcones and hydrazine as potential antitumor and antimalarial agents
Braulio Insuasty et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation
Man Zou et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Synthesis, characterization, and biological evaluation of certain 1,3-thiazolone derivatives bearing pyrazoline moiety as potential anti-breast cancer agents
Nadia A. Khalil et al.
MEDICINAL CHEMISTRY RESEARCH (2013)
Photodynamic therapeutic effect of indocyanine green entrapped in polymeric nanoparticles and their anti-EGFR-conjugate in skin cancer in CD1 mice
Amira M. Gamal-Eldeen et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2013)
Molecular cytogenetic evaluation of the efficacy of photodynamic therapy by indocyanine green in breast adenocarcinoma MCF-7 cells
Mona A. M. Abo-Zeid et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2013)
Synthesis and Anticancer Activity of Isatin-Based Pyrazolines and Thiazolidines Conjugates
Dmytro Havrylyuk et al.
ARCHIV DER PHARMAZIE (2011)
1-[(2-Arylthiazol-4-yl)methyl]azoles as a New Class of Anticonvulsants: Design, Synthesis, In vivo Screening, and In silico Drug-like Properties
Nematollah Ahangar et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2011)
EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features
Feng Li et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
Critical and Diverse Involvement of Akt/Mammalian Target of Rapamycin Signaling in Human Lung Carcinomas
Yoh Dobashi et al.
CANCER (2009)
Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: An analogue-based drug design approach
Ritesh N. Sharma et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)
The development of HKI-272 and related compounds for the treatment of cancer
Allan Wissner et al.
ARCHIV DER PHARMAZIE (2008)
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas
Christina Magkou et al.
BREAST CANCER RESEARCH (2008)
Epidermal growth factor receptor signaling modulates apoptosis via p38α MAPK-dependent activation of Bax in intestinal epithelial cells
George Sheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272
Y. Minami et al.
ONCOGENE (2007)
Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
H Asanuma et al.
CANCER RESEARCH (2005)
Getitinib (ZD1839, Iressa®) in non-small-cell lung cancer:: a review of clinical trials from a daily practice perspective
F Barlési et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2005)
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
R Sordella et al.
SCIENCE (2004)
Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase
SK Rabindran et al.
CANCER RESEARCH (2004)