4.4 Article

Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cthGAMP

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Single Crystals Heterogeneity Impacts the Intrinsic and Extrinsic Properties of Metal-Organic Frameworks

Adrian Fuchs et al.

Summary: This study addresses the gap between the crystal structure of a material and its bulk properties by using optical microscopy and spectroscopy for the correlative analysis of metal-organic framework particles in situ. The authors demonstrate that the crystal shape strongly impacts optical absorption and discuss the distribution and adsorption of water within MOF-801. The results highlight the importance of particle level characterization in understanding material properties.

ADVANCED MATERIALS (2022)

Review Immunology

The cGAS-STING pathway as a therapeutic target in inflammatory diseases

Alexiane Decout et al.

Summary: The cGAS-STING signaling pathway plays a crucial role in inflammation in infection, cellular stress, and tissue damage settings. It has the ability to sense and regulate cellular responses to DNA and has the potential to be targeted in the treatment of various inflammatory diseases.

NATURE REVIEWS IMMUNOLOGY (2021)

Article Biochemistry & Molecular Biology

Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis

Yao Li et al.

CHEMBIOCHEM (2020)

Article Biochemistry & Molecular Biology

Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis

Joseph Sarhan et al.

CELL DEATH AND DIFFERENTIATION (2019)

Article Multidisciplinary Sciences

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders

Liudmila Andreeva et al.

NATURE (2017)

Article Multidisciplinary Sciences

Signalling strength determines proapoptotic functions of STING

Muhammet F. Gulen et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Cyclic Dinucleotides and the Innate Immune Response

Olga Danilchanka et al.

Article Multidisciplinary Sciences

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser et al.

NATURE (2013)

Review Microbiology

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

Ute Romling et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2013)

Article Chemistry, Multidisciplinary

Emissive RNA Alphabet

Dongwon Shin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Biochemistry & Molecular Biology

Synthesis of cyclic di-nucleotidic acids as potential inhibitors targeting diguanylate cyclase

Shi Min Ching et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Review Chemistry, Multidisciplinary

Fluorescent Analogs of Biomolecular Building Blocks: Design, Properties, and Applications

Renatus W. Sinkeldam et al.

CHEMICAL REVIEWS (2010)

Article Biophysics

The phasor approach to fluorescence lifetime imaging analysis

Michelle A. Digman et al.

BIOPHYSICAL JOURNAL (2008)

Article Multidisciplinary Sciences

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa et al.

NATURE (2008)

Article Biochemical Research Methods

Polar plot representation for frequency-domain analysis of fluorescence lifetimes

GI Redford et al.

JOURNAL OF FLUORESCENCE (2005)