4.6 Article

Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Selective vulnerability of inhibitory networks in multiple sclerosis

Lida Zoupi et al.

Summary: Neurodegeneration in multiple sclerosis may affect specific neuronal components early on, and could be a result of demyelination.

ACTA NEUROPATHOLOGICA (2021)

Article Clinical Neurology

Epileptic seizures in multiple sclerosis: prevalence, competing causes and diagnostic accuracy

Friederike Neuss et al.

Summary: This study described a cohort of patients with both MS and epileptic seizures, finding that a significant percentage of MS patients with seizures had competing causes at the time of the first seizure. A detailed diagnostic setup including patient history, EEG, and MRI is recommended for evaluation and treatment decisions.

JOURNAL OF NEUROLOGY (2021)

Review Chemistry, Medicinal

Epilepsy in Neurodegenerative Diseases: Related Drugs and Molecular Pathways

Amanda Cano et al.

Summary: Epilepsy is a chronic disease of the central nervous system characterized by an electrical imbalance in neurons. The molecular processes that trigger epileptic seizures and promote neurotoxic effects are currently focused on the glutamate pathway and influx of calcium ions into neurons. Common molecular links between epilepsy and other neurodegenerative diseases have led to investigation of antiseizure drugs for therapeutic potential in these pathologies.

PHARMACEUTICALS (2021)

Article Pharmacology & Pharmacy

The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target

Qays Kharouf et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Article Clinical Neurology

Central Neuropathic Pain and Profiles of Quantitative Electroencephalography in Multiple Sclerosis Patients

Nataliya A. Krupina et al.

FRONTIERS IN NEUROLOGY (2020)

Review Cell Biology

The Cuprizone Model: Dos and Do Nots

Jiangshan Zhan et al.

CELLS (2020)

Article Immunology

Myelination- and immune-mediated MR-based brain network correlates

Manuela Cerina et al.

JOURNAL OF NEUROINFLAMMATION (2020)

Review Neurosciences

Dynamic Responses of Microglia in Animal Models of Multiple Sclerosis

Melanie J. Plastini et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2020)

Article Chemistry, Medicinal

EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues

Maria Novella Romanelli et al.

ACS MEDICINAL CHEMISTRY LETTERS (2019)

Article Medicine, Research & Experimental

Distinct Topographical Patterns of Spike-Wave Discharge in Transgenic and Pharmacologically Induced Absence Seizure Models

Soojung Lee et al.

EXPERIMENTAL NEUROBIOLOGY (2019)

Article Neurosciences

The Brain Network in a Model of Thalamocortical Dysrhythmia

Mehrnoush Zobeiri et al.

BRAIN CONNECTIVITY (2019)

Article Neurosciences

Neuroinflammation Alters Integrative Properties of Rat Hippocampal Pyramidal Cells

Federica Frigerio et al.

MOLECULAR NEUROBIOLOGY (2018)

Article Neurosciences

Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides

Maia Datunashvili et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2018)

Article Anatomy & Morphology

Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels

Mehrnoush Zobeiri et al.

BRAIN STRUCTURE & FUNCTION (2018)

Review Clinical Neurology

Targeting B cells in relapsing-remitting multiple sclerosis: from pathophysiology to optimal clinical management

Stefan Bittner et al.

THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2017)

Article Immunology

Inflammatory demyelination alters subcortical visual circuits

Sheila Espirito Santo Araujo et al.

JOURNAL OF NEUROINFLAMMATION (2017)

Article Neurosciences

CHRONIC DEMYELINATION-INDUCED SEIZURES

Andrew S. Lapato et al.

NEUROSCIENCE (2017)

Article Behavioral Sciences

Unprovoked seizures in multiple sclerosis: Why are they rare?

Anamarija Kavcic et al.

BRAIN AND BEHAVIOR (2017)

Review Pharmacology & Pharmacy

Novel Treatment and New Drugs in Epilepsy Treatment

Elissavet Eskioglou et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Article Clinical Neurology

Epilepsy in multiple sclerosis A nationwide population-based register study

Joachim Burman et al.

NEUROLOGY (2017)

Article Immunology

Thalamocortical-auditory network alterations following cuprizone-induced demyelination

Nikoo Ghaffarian et al.

JOURNAL OF NEUROINFLAMMATION (2016)

Article Multidisciplinary Sciences

Covariation of axon initial segment location and dendritic tree normalizes the somatic action potential

Mustafa S. Hamada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Immunology

Astrocytes: Key Regulators of Neuroinflammation

Emanuela Colombo et al.

TRENDS IN IMMUNOLOGY (2016)

Review Biochemistry & Molecular Biology

Thalamus pathology in multiple sclerosis: from biology to clinical application

Markus Kipp et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Physiology

Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy

Stuart M. Cain et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)

Article Neurosciences

Elevation in Type I Interferons Inhibits HCN1 and Slows Cortical Neuronal Oscillations

Konstantin Stadler et al.

CEREBRAL CORTEX (2014)

Article Biochemistry & Molecular Biology

Progress and Outlooks in a Genetic Absence Epilepsy Model (WAG/Rij)

G. Luijtelaar et al.

CURRENT MEDICINAL CHEMISTRY (2014)

Review Immunology

Oligodendrocyte-microglia cross-talk in the central nervous system

Laura Peferoen et al.

IMMUNOLOGY (2014)

Review Behavioral Sciences

Cellular and molecular neuropathology of the cuprizone mouse model: Clinical relevance for multiple sclerosis

Jelle Praet et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)

Article Neurosciences

Interleukin-1β and interleukin-6 affect electrophysiological properties of thalamic relay cells

Vinicius Nikolaos Samios et al.

NEUROSCIENCE RESEARCH (2014)

Review Physiology

Role for T-type Ca2+ channels in sleep waves

Vincenzo Crunelli et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)

Review Neurosciences

Neurophysiology of HCN channels: From cellular functions to multiple regulations

Chao He et al.

PROGRESS IN NEUROBIOLOGY (2014)

Review Immunology

A critical role for interleukin-1β in the progression of autoimmune diseases

Ruijuan Zhao et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2013)

Article Biochemistry & Molecular Biology

Cuprizone-Induced Demyelination as a Tool to Study Remyelination and Axonal Protection

Adib Zendedel et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2013)

Article Neurosciences

Pathology of Multiple Sclerosis

Markus Kipp et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2012)

Editorial Material Cell Biology

Neurofilaments at a glance

Aidong Yuan et al.

JOURNAL OF CELL SCIENCE (2012)

Article Biochemistry & Molecular Biology

Adenylyl Cyclases: Expression in the Developing Rat Thalamus and Their Role in Absence Epilepsy

Petra Ehling et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2012)

Article Neurosciences

Cytokines and Absence Seizures in a Genetic Rat Model

G. van Luijtelaar et al.

NEUROPHYSIOLOGY (2012)

Review Physiology

From sleep spindles of natural sleep to spike and wave discharges of typical absence seizures: is the hypothesis still valid?

Nathalie Leresche et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2012)

Review Biochemistry & Molecular Biology

Role of microglia in CNS inflammation

Manuel B. Graeber et al.

FEBS LETTERS (2011)

Review Biochemistry & Molecular Biology

HCN channels: Structure, cellular regulation and physiological function

C. Wahl-Schott et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2009)

Article Clinical Neurology

Development of spike-wave seizures in C3H/HeJ mice

Damien J. Ellens et al.

EPILEPSY RESEARCH (2009)

Review Physiology

Hyperpolarization-Activated Cation Channels: From Genes to Function

Martin Biel et al.

PHYSIOLOGICAL REVIEWS (2009)

Article Pathology

Cortical demyelination is prominent in the murine cuprizone model and is strain-dependent

Thomas Skripuletz et al.

AMERICAN JOURNAL OF PATHOLOGY (2008)

Article Neurosciences

Epileptic seizures and hippocampal damage after cuprizone-induced demyelination in C57BL/6 mice

Katrin Hoffmann et al.

EXPERIMENTAL NEUROLOGY (2008)

Article Biochemistry & Molecular Biology

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4

Barbara Beyer et al.

HUMAN MOLECULAR GENETICS (2008)

Article Clinical Neurology

Extensive cortical inflammation is associated with epilepsy in multiple sclerosis

Massimiliano Calabrese et al.

JOURNAL OF NEUROLOGY (2008)

Article Clinical Neurology

Amygdala kindling in the WAG/Rij rat model of absence epilepsy

RG Aker et al.

EPILEPSIA (2006)

Article Multidisciplinary Sciences

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain

H Rus et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Clinical Neurology

Evolving concepts on the pathophysiology of absence seizures - The cortical focus theory

H Meeren et al.

ARCHIVES OF NEUROLOGY (2005)

Review Behavioral Sciences

Epilepsy and multiple sclerosis

CM Poser et al.

EPILEPSY & BEHAVIOR (2003)

Article Biochemistry & Molecular Biology

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

A Ludwig et al.

EMBO JOURNAL (2003)

Review Clinical Neurology

NEURON: A tool for neuroscientists

ML Hines et al.

NEUROSCIENTIST (2001)

Article Neurosciences

Topography of EEG dynamics after sleep deprivation in mice

R Huber et al.

JOURNAL OF NEUROPHYSIOLOGY (2000)

Article Clinical Neurology

Electroencephalographic coherence analysis in multiple sclerosis: correlation with clinical, neuropsychological, and MRI findings

L Leocani et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2000)

Article Clinical Neurology

Neurophysiological investigations in multiple sclerosis

L Leocani et al.

CURRENT OPINION IN NEUROLOGY (2000)