4.5 Article

CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells

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Summary: This study investigated the epigenetic regulation of Treg cells, demonstrating that demethylation of TSDR can induce FOXP3 expression but is not sufficient for stable induction of functional Treg cell phenotype.

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