4.7 Article

Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Selectively targeting disease-restricted secretogranin III to alleviate choroidal neovascularization

Liyang Ji et al.

Summary: Choroidal neovascularization (CNV), a leading cause of blindness in the elderly, is commonly treated with vascular endothelial growth factor (VEGF) inhibitors, but these therapies have limited efficacy and potential side effects. This study explores the potential of secretogranin III (Scg3) as a disease-selective angiogenic factor for the treatment of CNV. The researchers found that Scg3 binds specifically to CNV vessels and its neutralization inhibits CNV. The combination of an anti-Scg3 antibody and a VEGF inhibitor showed synergistic effects in alleviating CNV. These findings suggest that Scg3 could be a next-generation targeted therapy for CNV.

FASEB JOURNAL (2022)

Review Biochemistry & Molecular Biology

Concurrent Physiological and Pathological Angiogenesis in Retinopathy of Prematurity and Emerging Therapies

Chang Dai et al.

Summary: Retinopathy of prematurity (ROP) is an ocular vascular disease that affects premature infants, characterized by pathological retinal neovascularization, dilated and tortuous retinal blood vessels, and retinal or vitreous hemorrhages. Current treatments include laser or cryotherapy, but there is ongoing research looking into selectively inhibiting pathological angiogenesis while promoting physiological angiogenesis in the treatment of ROP.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Urology & Nephrology

Targeting angiogenesis and lymphangiogenesis in kidney disease

Katsuyuki Tanabe et al.

NATURE REVIEWS NEPHROLOGY (2020)

Article Multidisciplinary Sciences

VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons

Nicolas Froger et al.

SCIENTIFIC REPORTS (2020)

Article Ophthalmology

Function-first ligandomics for ocular vascular research and drug target discovery

Xin Rong et al.

EXPERIMENTAL EYE RESEARCH (2019)

Article Peripheral Vascular Disease

Anti-secretogranin III therapy of oxygen-induced retinopathy with optimal safety

Fen Tang et al.

ANGIOGENESIS (2019)

Article Ophthalmology

Secretogranin III as a novel target for the therapy of choroidal neovascularization

Michelle E. LeBlanc et al.

EXPERIMENTAL EYE RESEARCH (2019)

Review Oncology

Contribution of Angiogenesis to Inflammation and Cancer

Dolores Aguilar-Cazares et al.

FRONTIERS IN ONCOLOGY (2019)

Review Pharmacology & Pharmacy

Ligandomics: a paradigm shift in biological drug discovery

Wei Li et al.

DRUG DISCOVERY TODAY (2018)

Article Biochemistry & Molecular Biology

Adenosine A2A receptor antagonists act at the hyperoxic phase to confer protection against retinopathy

Rong Zhou et al.

MOLECULAR MEDICINE (2018)

Review Health Care Sciences & Services

Bleeding in cancer patients and its treatment: a review

Candice Johnstone et al.

ANNALS OF PALLIATIVE MEDICINE (2018)

Review Biochemistry & Molecular Biology

Secretogranin III: a diabetic retinopathy-selective angiogenic factor

Wei Li et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Article Biochemistry & Molecular Biology

CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis

Anisyah Ridiandries et al.

FASEB JOURNAL (2017)

Article Immunology

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy

Michelle E. LeBlanc et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Endocrinology & Metabolism

Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis

Jonathan D. Lam et al.

DIABETES (2017)

Article Medicine, Research & Experimental

Targeting prion-like protein doppel selectively suppresses tumor angiogenesis

Taslim A. Al-Hilal et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Ophthalmology

Molecular pathogenesis of retinal and choroidal vascular diseases

Peter A. Campochiaro

PROGRESS IN RETINAL AND EYE RESEARCH (2015)

Article Ophthalmology

Effects of Anti-VEGF Treatment on the Recovery of the Developing Retina Following Oxygen-Induced Retinopathy

Clayton C. Tokunaga et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

Article Medicine, General & Internal

Retinopathy of prematurity

Ann Hellstrom et al.

LANCET (2013)

Article Multidisciplinary Sciences

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues

Yunlong Yanga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Intravital analysis of vascular permeability in mice using two-photon microscopy

Gyohei Egawa et al.

SCIENTIFIC REPORTS (2013)

Review Pharmacology & Pharmacy

Angiogenesis and Microvasculature in the Female Reproductive Organs: Physiological and Pathological Implications

Takashi Shimizu et al.

CURRENT PHARMACEUTICAL DESIGN (2012)

Article Pharmacology & Pharmacy

Bevacizumab-induced serious side-effects: a review of the French pharmacovigilance database

Solene Taugourdeau-Raymond et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2012)

Review Cell Biology

Developmental and Pathological Angiogenesis

Alicia S. Chung et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)

Article Developmental Biology

Signal transduction in vasculogenesis and developmental angiogenesis

Sunita Patel-Hett et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2011)

Article Ophthalmology

Effect of VEGF Trap on Normal Retinal Vascular Development and Oxygen-Induced Retinopathy in the Dog

Gerard A. Lutty et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Biochemistry & Molecular Biology

Efficient identification of tubby-binding proteins by an improved system of T7 phage display

Nora B. Caberoy et al.

JOURNAL OF MOLECULAR RECOGNITION (2010)

Article Ophthalmology

Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: Same or different disease?

Augustinus Laude et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2010)

Article Multidisciplinary Sciences

CCR3 is a target for age-related macular degeneration diagnosis and therapy

Atsunobu Takeda et al.

NATURE (2009)

Article Multidisciplinary Sciences

Dendrites of rod bipolar cells sprout in normal aging retina

Lauren C. Liets et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)