Related references
Note: Only part of the references are listed.Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor
Sylwia Bartoszewska et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2021)
Genome-wide mRNA profiling identifies RCAN1 and GADD45A as regulators of the transitional switch from survival to apoptosis during ER stress
Rafal Bartoszewski et al.
FEBS JOURNAL (2020)
mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion
Brian T. Gaudette et al.
NATURE COMMUNICATIONS (2020)
IRE1 Endoribonuclease Activity Modulates Hypoxic HIF-1α Signaling in Human Endothelial Cells
Adrianna Moszynska et al.
BIOMOLECULES (2020)
Induction of early growth response gene 1 (EGR1) by endoplasmic reticulum stress is mediated by the extracellular regulated kinase (ERK) arm of the MAPK pathways
Jixiu Shan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer
Carter J. Barger et al.
CANCERS (2019)
miR-34c-5p modulates X-box-binding protein 1 (XBP1) expression during the adaptive phase of the unfolded protein response
Sylwia Bartoszewska et al.
FASEB JOURNAL (2019)
Key genes associated with diabetes mellitus and hepatocellular carcinoma
Gao-Min Liu et al.
PATHOLOGY RESEARCH AND PRACTICE (2019)
Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
Anna Shemorry et al.
ELIFE (2019)
Systematic interrogation of human promoters
Shira Weingarten-Gabbay et al.
GENOME RESEARCH (2019)
Widespread PERK-dependent repression of ER targets in response to ER stress
Nir Gonen et al.
SCIENTIFIC REPORTS (2019)
Ensembl 2018
Daniel R. Zerbino et al.
NUCLEIC ACIDS RESEARCH (2018)
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
Chih-Hang Anthony Tang et al.
JOURNAL OF CELL BIOLOGY (2018)
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
Tsun-Kai Chang et al.
MOLECULAR CELL (2018)
PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells
Magdalena Gebert et al.
SCIENTIFIC REPORTS (2018)
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
Diego Acosta-Alvear et al.
ELIFE (2018)
miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells
Rafal Bartoszewski et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2017)
The effects of care bundles on patient outcomes: a systematic review and meta-analysis
Jacqueline F. Lavallee et al.
IMPLEMENTATION SCIENCE (2017)
miR-200b downregulates CFTR during hypoxia in human lung epithelial cells
Sylwia Bartoszewska et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2017)
BCL-2 family: integrating stress responses at the ER to control cell demise
Philippe Pihan et al.
CELL DEATH AND DIFFERENTIATION (2017)
Cell death induced by endoplasmic reticulum stress
Raffaella Iurlaro et al.
FEBS JOURNAL (2016)
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
Maxim V. Kuleshov et al.
NUCLEIC ACIDS RESEARCH (2016)
Divergence and Conservation of the Major UPR Branch IRE1-bZIP Signaling Pathway across Eukaryotes
Lingrui Zhang et al.
SCIENTIFIC REPORTS (2016)
Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway
Akio Tsuru et al.
SCIENTIFIC REPORTS (2016)
InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
Henry Heberle et al.
BMC BIOINFORMATICS (2015)
The unfolded protein response is shaped by the NMD pathway
Rachid Karam et al.
EMBO REPORTS (2015)
Proteostasis control by the unfolded protein response
Claudio Hetz et al.
NATURE CELL BIOLOGY (2015)
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
Min Lu et al.
SCIENCE (2014)
The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity
J. A. Wali et al.
CELL DEATH & DISEASE (2014)
When ER stress reaches a dead end
Hery Urra et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
ER stress-induced cell death mechanisms
Renata Sano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
Identification of a Novel Endoplasmic Reticulum Stress Response Element Regulated by XBP1
Michael Misiewicz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
IRE1: ER stress sensor and cell fate executor
Yani Chen et al.
TRENDS IN CELL BIOLOGY (2013)
Nencki Genomics Database-Ensembl funcgen enhanced with intersections, user data and genome-wide TFBS motifs
Izabella Krystkowiaky et al.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION (2013)
Generation of Stable Human Cell Lines with Tetracycline-inducible (Tet-on) shRNA or cDNA Expression
Marta Gomez-Martinez et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
Genetically defining the mechanism of Puma- and Bim-induced apoptosis
S. P. Garrison et al.
CELL DEATH AND DIFFERENTIATION (2012)
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
T. Verfaillie et al.
CELL DEATH AND DIFFERENTIATION (2012)
NOXA contributes to the sensitivity of PERK-deficient cells to ER stress
Sanjeev Gupta et al.
FEBS LETTERS (2012)
DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins
Sujan Piya et al.
FEBS LETTERS (2012)
The impact of the unfolded protein response on human disease
Shiyu Wang et al.
JOURNAL OF CELL BIOLOGY (2012)
A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation
Mithu Majumder et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
Benedict C. S. Cross et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity
Andrew Byrd et al.
Cells (2012)
Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
Feng-Ming Wang et al.
BIOCHEMICAL JOURNAL (2011)
Signaling cell death from the endoplasmic reticulum stress response
Gordon C. Shore et al.
CURRENT OPINION IN CELL BIOLOGY (2011)
p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis
Jaemin Lee et al.
NATURE MEDICINE (2011)
Translational Pausing Ensures Membrane Targeting and Cytoplasmic Splicing of XBP1u mRNA
Kota Yanagitani et al.
SCIENCE (2011)
SUMO modification regulates the transcriptional activity of XBP1
Hui Chen et al.
BIOCHEMICAL JOURNAL (2010)
Caspase-7: A protease involved in apoptosis and inflammation
Mohamed Lamkanfi et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress
Esteban N. Gurzov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Cole Trapnell et al.
NATURE BIOTECHNOLOGY (2010)
Identification of a consensus element recognized and cleaved by IRE1α
Daisuke Oikawa et al.
NUCLEIC ACIDS RESEARCH (2010)
Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim
A. M. Jabbour et al.
CELL DEATH AND DIFFERENTIATION (2009)
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
Aya Uemura et al.
JOURNAL OF CELL SCIENCE (2009)
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
J. Li et al.
CELL DEATH AND DIFFERENTIATION (2008)
The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response
Rafal Bartoszewski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
BH3-only proteins and their roles in programmed cell death
M. Giam et al.
ONCOGENE (2008)
Lentivirus as a tool for lineage-specific gene manipulations (vol 45, pg 456, 2007)
Anna Malashicheva et al.
GENESIS (2007)
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
Keisuke Yamamoto et al.
DEVELOPMENTAL CELL (2007)
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
Diego Acosta-Alvear et al.
MOLECULAR CELL (2007)
MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
Andrew Grimson et al.
MOLECULAR CELL (2007)
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
Simon N. Willis et al.
SCIENCE (2007)
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
D. Thomas Rutkowski et al.
PLOS BIOLOGY (2006)
Cytoplasmic IRE1α-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress
Sung Hoon Back et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Endoplasmic reticulum stress-induced apoptosis - Multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
JZ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response
B Tirosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
H Yoshida et al.
JOURNAL OF CELL BIOLOGY (2006)
Mediators of endoplasmic reticulum stress-induced apoptosis
Eva Szegezdi et al.
EMBO REPORTS (2006)
ER stress and the unfolded protein response
M Schröder et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)
Roles of CHOP/GADD153 in endoplasmic reticulum stress
S Oyadomari et al.
CELL DEATH AND DIFFERENTIATION (2004)
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
AL Shaffer et al.
IMMUNITY (2004)
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death
J Hitomi et al.
JOURNAL OF CELL BIOLOGY (2004)
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1α to the endoplasmic reticulum and promotes dephosphorylation of the α subunit of eukaryotic translation initiation factor 2
MH Brush et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
AH Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The endoplasmic reticulum: a multifunctional signaling organelle
MJ Berridge
CELL CALCIUM (2002)
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
JS Shen et al.
DEVELOPMENTAL CELL (2002)
IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
K Lee et al.
GENES & DEVELOPMENT (2002)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
PERK mediates cell-cycle exit during the mammalian unfolded protein response
JW Brewer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)