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ONCOTARGET (2016)
GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers
How-Wen Ko et al.
ONCOTARGET (2016)
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
Nikos Papakonstantinou et al.
ONCOTARGET (2016)
Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis
Chi-Yeh Chung et al.
CELL REPORTS (2016)
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis
Vincent van den Boom et al.
CELL REPORTS (2016)
The BAH domain of BAHD1 is a histone H3K27me3 reader
Dan Zhao et al.
PROTEIN & CELL (2016)
Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers
Ji-Hyun Lee et al.
CELL DISCOVERY (2016)
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
David Castel et al.
ACTA NEUROPATHOLOGICA (2015)
S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells
Tsang-Pai Liu et al.
ANTI-CANCER DRUGS (2015)
Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis
Stanley C. W. Lee et al.
BLOOD (2015)
Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner
Makiko Mochizuki-Kashio et al.
BLOOD (2015)
Polycomb Regulates Mesoderm Cell Fate-Specification in Embryonic Stem Cells through Activation and Repression Mechanisms
Lluis Morey et al.
CELL STEM CELL (2015)
Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain
Chunyan Ren et al.
CHEMISTRY & BIOLOGY (2015)
Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2
Stephen G. Dann et al.
EMBO JOURNAL (2015)
Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis
Michel Wassef et al.
GENES & DEVELOPMENT (2015)
Recruiting polycomb to chromatin
Ha van Kruijsbergen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma
Jiro Kikuchi et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches
V. D'Angelo et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome
Stefan Schoenfelder et al.
NATURE GENETICS (2015)
Loss of BAP1 function leads to EZH2-dependent transformation
Lindsay M. LaFave et al.
NATURE MEDICINE (2015)
PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression
Junhu Wan et al.
NUCLEIC ACIDS RESEARCH (2015)
MicroRNA-195-5p acts as an anti-oncogene by targeting PHF19 in hepatocellular carcinoma
Hui Xu et al.
ONCOLOGY REPORTS (2015)
Prognostic significance of Cbx4 expression and its beneficial effect for transarterial chemoembolization in hepatocellular carcinoma
H-K Jiao et al.
CELL DEATH & DISEASE (2015)
BMI-1, a promising therapeutic target for human cancer (Review)
Min-Cong Wang et al.
ONCOLOGY LETTERS (2015)
Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex
Anand Balasubramani et al.
NATURE COMMUNICATIONS (2015)
Dual Roles of RNF2 in Melanoma Progression
Kunal Rai et al.
CANCER DISCOVERY (2015)
MEL-18, a tumor suppressor for aggressive breast cancer
Jeong-Yeon Lee et al.
ONCOTARGET (2015)
Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer
Yan-Long Liu et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)
Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation
A. A. Sahasrabuddhe et al.
ONCOGENE (2015)
HP1 beta Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy
Young-Ho Lee et al.
PLOS ONE (2015)
Estrogen receptor α-coupled Bmi1 regulation pathway in breast cancer and its clinical implications
Huali Wang et al.
BMC CANCER (2014)
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS
Roberta Ciarapica et al.
BMC CANCER (2014)
Cbx4 Governs HIF-1α to Potentiate Angiogenesis of Hepatocellular Carcinoma by Its SUMO E3 Ligase Activity
Jie Li et al.
CANCER CELL (2014)
NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Filippos Kottakis et al.
CANCER RESEARCH (2014)
Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
Neil P. Blackledge et al.
CELL (2014)
Polycomb Repressive Complex 2 Regulates Normal Hematopoietic Stem Cell Function in a Developmental-Stage-Specific Manner
Huafeng Xie et al.
CELL STEM CELL (2014)
Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing
Feng Tie et al.
DEVELOPMENT (2014)
Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma
Barbara Dewaele et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Histone Methyltransferase EZH2 Is Transcriptionally Induced by Estradiol as Well as Estrogenic Endocrine Disruptors Bisphenol-A and Diethylstilbestrol
Arunoday Bhan et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins
Rong-gang Ma et al.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2014)
Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide
Eva Madi Riising et al.
MOLECULAR CELL (2014)
Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity
Karin J. Ferrari et al.
MOLECULAR CELL (2014)
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
S. C. Mack et al.
NATURE (2014)
An AUTS2-Polycomb complex activates gene expression in the CNS
Zhonghua Gao et al.
NATURE (2014)
Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma
Jessica Okosun et al.
NATURE GENETICS (2014)
JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells
Z. S. Walters et al.
ONCOGENE (2014)
Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer
J-Y Lee et al.
ONCOGENE (2014)
O-GlcNAcylation regulates EZH2 protein stability and function
Chi-Shuen Chu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis
Shan-Shan Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling
Hans-Martin Herz et al.
SCIENCE (2014)
Suppressor of Zeste 12 homolog RNA interference inhibits retinoblastoma cell invasion
Min Zhou et al.
ONCOLOGY LETTERS (2014)
The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells
Almudena Bosch et al.
ONCOTARGET (2014)
Regulation and Role of EZH2 in Cancer
Hirohito Yamaguchi et al.
CANCER RESEARCH AND TREATMENT (2014)
EZH2-Mediated Inactivation of IFN-γ-JAK-STAT1 Signaling Is an Effective Therapeutic Target in MYC-Driven Prostate Cancer
Zhen Ning Wee et al.
CELL REPORTS (2014)
EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity
Junli Yan et al.
BLOOD (2013)
EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Wendy Beguelin et al.
CANCER CELL (2013)
Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
Sebastian Bender et al.
CANCER CELL (2013)
Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
Eunhee Kim et al.
CANCER CELL (2013)
CBX8 suppresses Sirtinol-induced premature senescence in human breast cancer cells via cooperation with SIRT1
Sang Hyup Lee et al.
CANCER LETTERS (2013)
Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke
Yung-Luen Yu et al.
EMBO MOLECULAR MEDICINE (2013)
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
Kui-Ming Chan et al.
GENES & DEVELOPMENT (2013)
RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12)
Ioannis Panagopoulos et al.
GENES CHROMOSOMES & CANCER (2013)
BMI1, The polycomb-group gene, is recurrently targeted by genomic rearrangements in progressive B-cell leukemia/lymphoma
Leila Rouhigharabaei et al.
GENES CHROMOSOMES & CANCER (2013)
Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders
Tomoya Muto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes
Alberto Frangini et al.
MOLECULAR CELL (2013)
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
Jin He et al.
NATURE CELL BIOLOGY (2013)
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
Sam Behjati et al.
NATURE GENETICS (2013)
Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme
Gang Li et al.
PLOS ONE (2013)
A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb
Ana Raquel Pengelly et al.
SCIENCE (2013)
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
Peter W. Lewis et al.
SCIENCE (2013)
RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells
Lluis Morey et al.
CELL REPORTS (2013)
Cohesin and Polycomb Proteins Functionally Interact to Control Transcription at Silenced and Active Genes
Cheri A. Schaaf et al.
PLOS GENETICS (2013)
Recurrent Rearrangement of the PHF1 Gene in Ossifying Fibromyxoid Tumors
Samuel Gebre-Medhin et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
PHF19 and Akt control the switch between proliferative and invasive states in melanoma
Stephanie Ghislin et al.
CELL CYCLE (2012)
Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs
Emily Brookes et al.
CELL STEM CELL (2012)
Loss of Mel-18 enhances breast cancer stem cell activity and tumorigenicity through activating Notch signaling mediated by the Wnt/TCF pathway
Hee-Young Won et al.
FASEB JOURNAL (2012)
Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk
Arie B. Brinkman et al.
GENOME RESEARCH (2012)
SUZ12 Promotes Human Epithelial Ovarian Cancer by Suppressing Apoptosis via Silencing HRK
Hua Li et al.
MOLECULAR CANCER RESEARCH (2012)
PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
Zhonghua Gao et al.
MOLECULAR CELL (2012)
Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors
Ming Yu et al.
MOLECULAR CELL (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
Gang Wu et al.
NATURE GENETICS (2012)
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
Panagiotis Ntziachristos et al.
NATURE MEDICINE (2012)
The Role of EZH2 in the Regulation of the Activity of Matrix Metalloproteinases in Prostate Cancer Cells
Yong Jae Shin et al.
PLOS ONE (2012)
PRC2/EED-EZH2 Complex Is Up-Regulated in Breast Cancer Lymph Node Metastasis Compared to Primary Tumor and Correlates with Tumor Proliferation In Situ
Hongxiang Yu et al.
PLOS ONE (2012)
EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
Kexin Xu et al.
SCIENCE (2012)
Polycomb-Like 3 Promotes Polycomb Repressive Complex 2 Binding to CpG Islands and Embryonic Stem Cell Self-Renewal
Julie Hunkapiller et al.
PLOS GENETICS (2012)
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
Damian B. Yap et al.
BLOOD (2011)
KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia
Jin He et al.
BLOOD (2011)
Regulation of chromatin by histone modifications
Andrew J. Bannister et al.
CELL RESEARCH (2011)
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
Daniel J. Grau et al.
GENES & DEVELOPMENT (2011)
Classical Hodgkin's lymphoma shows epigenetic features of abortive plasma cell differentiation
Volkhard Seitz et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
Cyclin-dependent Kinase 1 (CDK1)-mediated Phosphorylation of Enhancer of Zeste 2 (Ezh2) Regulates Its Stability
Susan C. Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer
Bao-Hong Guo et al.
MOLECULAR CANCER (2011)
L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure
Patrick Trojer et al.
MOLECULAR CELL (2011)
CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
Yongkun Wei et al.
NATURE CELL BIOLOGY (2011)
Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway
J-H Park et al.
ONCOGENE (2011)
A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
Alice Lebreton et al.
SCIENCE (2011)
Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms
M. Brecqueville et al.
BLOOD CANCER JOURNAL (2011)
Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer
Bethany N. Hannafon et al.
BREAST CANCER RESEARCH (2011)
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo
Sha Hu et al.
CANCER BIOLOGY & THERAPY (2010)
Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma
Shintaro Iwata et al.
CANCER SCIENCE (2010)
A Region of the Human HOXD Cluster that Confers Polycomb-Group Responsiveness
Caroline J. Woo et al.
CELL (2010)
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA
Syuzo Kaneko et al.
GENES & DEVELOPMENT (2010)
Bmi-1 is critical for the proliferation and invasiveness of gastric carcinoma cells
Wei Li et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2010)
BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer
Xiao-Wei Zhang et al.
MOLECULAR CANCER (2010)
Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination
Ragnhild Eskeland et al.
MOLECULAR CELL (2010)
PAX5-AUTS2 fusion resulting from t(7;9)(q11.2;p13.2) can now be classified as recurrent in B cell acute lymphoblastic leukemia
E. Coyaud et al.
LEUKEMIA RESEARCH (2010)
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
Christopher J. Sneeringer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
J. William Harbour et al.
SCIENCE (2010)
Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain
Renjing Wang et al.
STRUCTURE (2010)
GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells
Eric M. Mendenhall et al.
PLOS GENETICS (2010)
A Vertebrate Polycomb Response Element Governs Segmentation of the Posterior Hindbrain
Angela Sing et al.
CELL (2009)
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
Feng Tie et al.
DEVELOPMENT (2009)
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling
Anne-Kathrin Classen et al.
NATURE GENETICS (2009)
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling
Anne-Marie Martinez et al.
NATURE GENETICS (2009)
Human BAHD1 promotes heterochromatic gene silencing
Helene Bierne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Loss of the CBX7 gene expression correlates with a highly malignant phenotype in thyroid cancer
Pierlorenzo Pallante et al.
CANCER RESEARCH (2008)
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation
Takeya Nakagawa et al.
GENES & DEVELOPMENT (2008)
Histione H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation
Wenlai Zhou et al.
MOLECULAR CELL (2008)
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains
Manching Ku et al.
PLOS GENETICS (2008)
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
Julie K. Stock et al.
NATURE CELL BIOLOGY (2007)
Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex
Chiara Lanzuolo et al.
NATURE CELL BIOLOGY (2007)
Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells
Bin Shi et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells
Wei-Jian Guo et al.
CANCER RESEARCH (2007)
Role of the chromobox protein CBX7 in lymphomagenesis
Clare L. Scott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
PHC3, a component of the hPRC-H complex, associates with E2F6 during G0 and is lost in osteosarcoma tumors
A. M. Deshpande et al.
ONCOGENE (2007)
Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins
Wei-Jian Guo et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
NSPc1 is a cell growth regulator that acts as a transcriptional repressor of p21Waf1/Cip1 via the RARE element
Yanhua Gong et al.
NUCLEIC ACIDS RESEARCH (2006)
Variability in the expression of polycomb proteins in different normal and tumoral tissues.: A pilot study using tissue microarrays
M Sánchez-Beato et al.
MODERN PATHOLOGY (2006)
Consistent rearrangement of chromosomal band 6p21 with generation of fusion genes JAZF1/PHF1 and EPC1/PHF1 in endometrial stromal sarcoma
F Micci et al.
CANCER RESEARCH (2006)
Akt-mediated phsophorylationof EZH2 suppresses methylation of lysine 27 in histone H3
TL Cha et al.
SCIENCE (2005)
CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus
D Bernard et al.
ONCOGENE (2005)
Polycomb silencing blocks transcription initiation
GI Dellino et al.
MOLECULAR CELL (2004)
Cytokines in cancer pathogenesis and cancer therapy
G Dranoff
NATURE REVIEWS CANCER (2004)
Chromatin compaction by a polycomb group protein complex
NJ Francis et al.
SCIENCE (2004)
Role of histone H2A ubiquitination in polycomb silencing
HB Wang et al.
NATURE (2004)
Structural basis for specific binding of polycomb chromodomain to histone H3 methylated at Lys 27
JR Min et al.
GENES & DEVELOPMENT (2003)
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
A Kuzmichev et al.
GENES & DEVELOPMENT (2002)
The polycomb group protein EZH2 is involved in progression of prostate cancer
S Varambally et al.
NATURE (2002)
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
SS Levine et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression
S Vonlanthen et al.
BRITISH JOURNAL OF CANCER (2001)