Tracing the origins of SARS-CoV-2: lessons learned from the past

Editorial Material Multidisciplinary Sciences

SARS-CoV-2 spillover events

Peng Zhou et al.

SCIENCE (2021)

Review Microbiology

Mink, SARS-CoV-2, and the Human-Animal Interface

Florence Fenollar et al.

Summary: Mink, small carnivores of the Mustelidae family, have been widely bred for their fur. Outbreaks of SARS-CoV-2 have been reported in mink farms in multiple countries, raising concerns about their potential role in the pandemic and the impact of mutant viruses on various aspects of the disease.

FRONTIERS IN MICROBIOLOGY (2021)

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Article Biochemistry & Molecular Biology

Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species

Kefang Liu et al.

Summary: Research has shown that the SARS-CoV-2 virus may originate from bats, with genetic sequences closely related to RaTG13. Experiments revealed that residue 501 plays a key role in determining the potential host range of RaTG13. Additionally, it was found that SARS-CoV-2 can induce strong cross-reactive antibodies and a monoclonal antibody capable of cross-neutralizing RaTG13.

CELL (2021)

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Article Public, Environmental & Occupational Health

Long Distance Transmission of SARS-CoV-2 from Contaminated Cold Chain Products to Humans - Qingdao City, Shandong Province, China, September 2020

Huilai Ma et al.

Summary: This report identified two dock workers in Qingdao, China with asymptomatic SARS-CoV-2 infection in September 2020. The workers were infected after contact with contaminated outer packaging, as confirmed by genomic sequencing. The study isolated infectious virus from cold chain products and emphasized the need for international cooperation to prevent virus contamination in various operations.

CHINA CDC WEEKLY (2021)

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Letter Biochemistry & Molecular Biology