Journal
CARBOHYDRATE POLYMERS
Volume 278, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2021.118998
Keywords
Polysaccharides; Agarose; Alginate; Chitosan; Cellulose; Dextran; Stimuli responsive; Electroconductive hydrogels; Tissue engineering; Flexible electronics; Drug delivery; Biomaterials
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Architecting a suitable platform for biomedical applications involves balancing simplicity and complexity. Polysaccharides (PSAs) are crucial in various aspects of our lives, including food resources, structural materials, and energy storage. They have also become indispensable ingredients in food and cosmetics. PSA-based hydrogels have been extensively studied in biomedical applications, showing optimal performance through different designs.
Architecting an appropriate platform for biomedical applications requires setting a balance between simplicity and complexity. Polysaccharides (PSAs) play essential roles in our life in food resources, structural materials, and energy storage capacitors. Moreover, the diversity and abundance of PSAs have made them an indispensable part of food ingredients and cosmetics. PSA-based hydrogels have been extensively reviewed in biomedical applications. These hydrogels can be designed in different forms to show optimum performance. For instance, electroactive PSA-based hydrogels respond under an electric stimulus. Such performance can be served in stimulus drug release and determining cell fate. This review classifies and discusses the structure, properties, and applications of the most important polysaccharide-based electroactive hydrogels (agarose, alginate, chitosan, cellulose, and dextran) in medicine, focusing on their usage in tissue engineering, flexible electronics, and drug delivery applications.
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