Related references
Note: Only part of the references are listed.Synthetic lethality as an engine for cancer drug target discovery
Alan Huang et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs
Marco Jost et al.
NATURE BIOTECHNOLOGY (2020)
Targeted Perturb-seq enables genome-scale genetic screens in single cells
Daniel Schraivogel et al.
NATURE METHODS (2020)
Development of KSQ-4279 as a first-in-class USP1 inhibitor for the treatment of BRCA-deficient cancers
L. Cadzow et al.
EUROPEAN JOURNAL OF CANCER (2020)
MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors
Thomas P. Howard et al.
CANCER RESEARCH (2019)
ADAR1: A New Target for Immuno-oncology Therapy
Amruta Bhate et al.
MOLECULAR CELL (2019)
WRN helicase is a synthetic lethal target in microsatellite unstable cancers
Edmond M. Chan et al.
NATURE (2019)
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens
Fiona M. Behan et al.
NATURE (2019)
Next-generation characterization of the Cancer Cell Line Encyclopedia
Mahmoud Ghandi et al.
NATURE (2019)
The landscape of cancer cell line metabolism
Haoxin Li et al.
NATURE MEDICINE (2019)
Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials
Ann Lin et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Pooled in vivo screens for cancer immunotherapy target discovery
Sarah K. Lane-Reticker et al.
IMMUNOTHERAPY (2018)
Genome-scale CRI SPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma
Bjorn Stolte et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
Robert T. Manguso et al.
NATURE (2017)
Defining a Cancer Dependency Map
Aviad Tsherniak et al.
CELL (2017)
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
Ying-Nan P. Chen et al.
NATURE (2016)
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
Raphael Ceccaldi et al.
NATURE (2015)
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Jordi Barretina et al.
NATURE (2012)
Share Paper
